This review of the influence of different regenerative techniques and materials on the outcome of endodontic surgery includes 11 RCTs. The findings suggest that regenerative approaches improve periapical lesion healing after endodontic surgery. However the studies are small and only 2 are at low risk of bias.
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This review of the effect of probiotics on gingival inflammation and oral microbiota in patients suffering from plaque-induced gingivitis included 11 RCTs. No clear evidence was found to indicate that oral probiotics have a positive effect on gingival inflammation and oral microecological environment of patients with gingivitis.
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This update of an earlier review of the malignant transformation rate of oral leukoplakia included 24 retrospective studies. The pooled proportion of malignant transformation was 9.8% (95%CI; 7.9 to 11.7%)
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Andrew Sommerlad appraises a recent review on the efficacy of interventions for depression in people with dementia, which identified several non-drug treatments that can have a meaningful effect on depressive symptoms in dementia.
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This review of systemic or locally delivered clarithromycin as an adjunct to non-surgical periodontal therapy included 7 small RCTs, 4 RCTS related to systemic use and 3RCTS for local application. The findings provide moderate certainty evidence suggesting locally delivered clarithromycin significantly improves treatment outcome
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Natalie Berry summarises a meta-analysis which finds a limited body of research exists to support the use of NHS e-therapies for depression, anxiety and stress.
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This review of whether plaque-disclosing (PD) methods, applied by dental professionals or at-home with verbal oral hygiene instruction (OHI)improved plaque control compared with OHI alone included 7 RCTs involving 430 patients.
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This diagnostic test accuracy review of visual classification systems for the detection and diagnosis of non-cavitated coronal dental caries in children or adults included 67 studies. The findings suggest that these classificationssystems have resonable performance but the certainty of the evidence is low.
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This review of the efficacy of rubber bristles interdental cleaners (RBIC) as an adjunct to toothbrushing (TB) included 6 RCTs. The findings provide weak to very weak certainty evidence for the use of RBICs for gingivitis and plaque reduction.
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The 2019 Bangkok Declaration defined early childhood caries (ECC) as the presence of a primary tooth with one or more carious (non-cavitated or cavitated lesions), missing (due to caries), or filled surfaces in a child under the age of six years. While dental caries is a preventable chronic health problem it remains a significant public [read the full story…]
