This review of the rate of malignant transformation (MT) of oral leukoplakia and potential risk factors included 26 mainly retrospective studies. The findings indicate a MT of 7.2% (95%CI; 5.40 to 9.10%) similar to those of another recent review whihc estimated MT as 9.8% (95%CI; 7.9 to 11.7%).
[read the full story...]
In her debut blog, Megan Bailey summarises an umbrella review of systematic reviews and meta-analyses on whether psychological trauma can be considered as a transdiagnostic risk factor for mental health disorders.
[read the full story...]
This review of virtual reality (VR) distraction interventions in alleviating dental anxiety in paediatric patients included 12 RCTs. The findings suggest VR could be an effective approach to alleviating dental anxiety in paediatric patients.
[read the full story...]
In her debut blog, Molly McCarthy appraises a recent Lancet Psychiatry systematic review and meta-analysis exploring the patterns of paediatric emergency department visits for suicide attempts, suicidal ideation, and self-harm incidents before and during the COVID-19 pandemic.
[read the full story...]
Éimear Foley summarises a recent meta-analysis, which looks at alteration patterns of peripheral concentrations of cytokines and associated inflammatory proteins in acute and chronic stages of schizophrenia.
[read the full story...]
This review comparing the effectiveness of different surgical methods for peri-implantitis included 13 parallel group RCTs. However, a wide variety of interventions were tested and the studies were generally small providing very low certainty evidence. Consequently additional high quality well reported studies are needed.
[read the full story...]
This review aimed to assess the effect of bioactive glass on bone and periodontal regeneration and included 20 RCTs. The included studies were small, involved numerous comparisions with only two being at low risk of bias. The findings showed a statistically signiciant benefit for probing depth with bioglass but this may not be clinically significant and the limited quality of thei included studies mean the findings should be interpreted cautiously.
[read the full story...]
This review of the failure rates of different orthodontic bonding materials included 80 studies with 34 contributing to the quantitative component. The findings suggest little difference between the self-etch primer and conventional acid-etch primer and a poorer performance for glass ionomer compared with self-cure resin. However the findings should be interpreted cautiously because of the low certainty of the available evidence.
[read the full story...]
In her debut blog, Laura Hankey summarises findings from a recent systematic review and meta-analysis investigating the effectiveness of internet-based interventions for depression and anxiety in children and young people.
[read the full story...]
This review of the efficacy of chlorhexidine (CHX) products in maintaining gingival health in orthodontic patients with fixed appliances included 20 RCTs only 1 of which was at low risk of bias. The findings showed a benefcial effect on gingival parameters with CHX mouthwash at 1-3 months but the findings should be interpreted cautiously.
[read the full story...]
