This review evaluating the preventive effect of regular applications of fluoride varnish (FV) on the development of white spot lesions (WSL) during orthodontic treatment included 7 RCTs. Meta-analyses demonstrated a reduction in the risk of WSL with regular FV applications but the certainty of evidence was very low.
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This review of pulpotomy ( partial or full) v root canal treatment (RoCT) in permanent teeth with pulpitis included 2 RCTs involving 957 teeth. The findings suggests no difference in pain at 7 days or in success rates at 1 and 5 years but the evidence is limited.
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This review of the efficacy of chewing gum in reducing pain intensity in patients undergoing fixed orthodontic treatment included 16 RCTs. The findings suggest , chewing gum was significantly more effective than both pharmacologic agents and placebo in reducing orthodontic pain 24 hours. However the evidence is of very low certainty.
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This review of the efficacy of mouthwashes on oral microorganisms and gingivitis in orthodontic patients included 32 RCTs. While the findings suggest short-term benefits with adjunctive mouthwash use the findings should be intertpreted cautiously as only one RCT was at low risk of bias and for almost all outccomes the certainty of evidence was rated as very low to low.
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This review comparing the effectiveness of a chewable toothbrush (CTB) with a manual toothbrush (MTB) in terms of plaque reduction included 7 RCTs. While no significant differences were found between CTB and MTB the availabel studies were small of short duration and of very low certainty.
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This review of periodontal health maintenance and gingival recessions development in patients undergoing an orthodontic treatment with clear aligners (CA) or fixed appliances (FA) included 12 studies. The limited amount and quality of evidence was insufficient to assess whether CA were bettern than FA at maintaining periodontal health.
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This review estimating the nocebo response in dentistry from trials of analgesic treatment following third molar surgery included data from 50 RCTs. Adverse events (AEs) were roughly the same in placebo and active arms suggesting AEs may be attributed to the nocebo phenomenon.
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This review and network meta-analysis (NMA) of pharmacological treatments for the management of pain subsequent to simple and surgical tooth extraction included 85 RCTs. There was moderate- and high-certainty evidence that for surgical dental extractions that ibuprofen 200 to 400 mg plus acetaminophen 500 to 1,000 mg was the most effective for pain relief.
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Camilla Babbage and Maria Loades summarise the largest meta-analysis to date on the effectiveness of CBT for depression.
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This review of patient-performed or administered measures used adjunctively to submarginal instrumentation for the management of peri-implant mucositis included 14 studies. The findings indicated that adjunctive measures reduced probing depth, bleeding on probing and plaque level reductions at 3 months and were in favour of adjunctive measures, which were plaque.
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