This review of the use of honey to educe the severity of radio/chemotherapy-induced oral mucositis identified 7 low quality RCTs that suggest that use of honey may reduce the severity of oral mucositis.
[read the full story...]
This review of the management of keratocystic odontogenic tumors included 14 mainly retrospective studies ans suggests that initial cystectomy, with or without adjuvant therapy, is associated with the least chance of recurrence.
[read the full story...]
This review the bleeding risk of patients continuing or discontinuing oral anticoagulant therapy found no increase bleeding risk in those continuing anticoagulant therapy.
[read the full story...]
The aim of this Cochrane review was to assess the effectiveness, safety and acceptability of treatments for oral leukoplakia in preventing oral cancer.
[read the full story...]
Six small RCTs were included in this review. Findings suggest that botulinum toxin type A (BoTN-A) has a positive effect on post treatment pain. Hover the results should be interpreted cautiously as the quality of the evidence is limited and more high quality studies are needed.
[read the full story...]
17 low quality studies were included in this review of the association between molar incisor hypomineralisation and caries. A significant association was suggested but none of the studies was considered to be of high quality so the findings should be interpreted with caution.
[read the full story...]
For this review of molar incisor hypomineralisation (MIH) 28 low quality studies were identified. The available evidence suggest that prenatal and perinatal factors are infrequently associated with MIH but that early childhood illness (in particular fever) may be associated.
[read the full story...]
This Cochrane review of bisphosphonate related osteonecrosis of the jaw only identified one small RCT. The trial compared the use of hyperbaric oxygen (HBO) as an adjunct to standard care. While it suggested a benefit for HBO it was under powered and at high riisk of bias
[read the full story...]
This Cochrane review looked at cryotherapy (ice chips) for preventing oral mucositis in patients with cancer. 14 RCTS involving 1280 patients were included providing evidence that oral cryotherapy leads to large reductions in oral mucositis of all severities in adults receiving 5FU for solid cancers. However there was less confidence confident in the ability of oral cryotherapy to reduce oral mucositis in adults receiving high-dose melphalan before haematopoietic stem cell transplantation (HSCT).
[read the full story...]
Dominic Hurst looks at the recent Cochrane review of interventions to help smokeless tobacco (ST) users quit. ST use is linked to oral cancer, precancer and periodontal disease, so dentists have an important role in encouraging users to quit.
[read the full story...]
