Results: 220

For: oral medicine and pathology

Benign parotid tumors: Superficial or total conservative parotidectomy

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13 retrospective studies were included in this review comparing superficial and total conservative parotidectomy approaches for the management of benign parotid tumours. The review suggests that superficial approach is better but the quality of the evidence is low.

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Bisphosphonate-related osteonecrosis of the jaw treatments

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97 papers describing 4879 cases of bisphosphonate-related osteonecrosis were included in this review. A wide range of management approaches were identified but the quality of the available evidence is limited.

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Avascular necrosis of the jaws (BRONJ): risk and incidence low in the UK

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This 2 year long prospective study of new cases of BRONJ presenting at oral surgery, oral medicine, oral and maxillofacial surgery units, and dental hospitals provides a rough estimate of 508–793 new cases/year across the UK.

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Photodynamic therapy: review finds insufficient evidence of its effectiveness for oral premalignant lesions

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This review of photodynamic therapy (PDT) for oral premalignant lesions only identified a small number of poor quality studies that provide insufficient evidence for the effectiveness of PDT for the management of oral premalignant lesions.

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Alcohol consumption increased oral cancer risk

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This new review investigated the effect of alcohol on 23 cancer types. They included 572 case-control and cohort studies and using meta-analysis and a dose–response meta-regression model found relative risks for heavy drinkers compared with nondrinkers and occasional drinkers were 5.13 for oral and pharyngeal cancer, 4.95 for oesophageal squamous cell carcinoma, 1.44 for colorectal, 2.65 for laryngeal and 1.61 for breast cancer.

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Zinc supplements may have some benefit in treating taste disorders

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Taste disorders can have a impact of health and quality of life. This new Cochrane review identified 9 trials (566 participants) and found some evidence that zinc supplements could improve taste perception in people with idiopathic taste disorders. However the evidence is not of high quality.

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Intravenous midazolam sedation for dental treatment: review found no significant side effects

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This review of IV midazolam for treating children and adolescents only identified 11 studies (5 RCTs, 6 non randomised). No serious adverse events were reported but there was a generalised inconsistency in side effect reporting. Consequently the call for better side effect reporting.

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Behçet’s disease: review found insufficient evidence to support or refute interventions for oral ulceration

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This review focuses on the treatment of oral ulceration in Behçet’s disease, 15 trials examining 13 different interventions were found. There was insufficient evidence to support or refute the use of any included intervention with regard to pain, episode duration, or episode frequency associated with oral ulcers, or safety of the interventions.

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Another review finds limited evidence for making treatment recommendations for keratocystic odontogenic tumors

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The keratocystic odontogenic tumor (KCOT) is a benign but locally aggressive tumour and accounts for 2-11% of jaw cysts and can occur at any age. Historically they have been referred to as odontogenic keratocyst (OKC) and primordial cyst. A range of treatment approaches have been suggested for KCOTs but preferred option is still debatable. The [read the full story…]

Insufficient evidence to determine the effect of systemic antibiotics on adults with symptomatic apical periodontitis or acute apical abscess

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The recommended treatment for apical periodontitis or acute apical abscess is removal of the source of inflammation or infection by local, operative measures ie tooth extraction or pulp extirpation possibly in combination with the incision and drainage of any swelling present. Antibiotics are only recommended where there is evidence of spreading infection or systemic symptoms.   [read the full story…]