Results: 41

For: oral cancer

New Cochrane Protocols February 2013


There are three new protocols on the February issue of the Cochrane Library The first protocol Carrasco-Labra A, Brignardello-Petersen R, Yanine N, Araya I, Rada G, Chadwick RG. Professionally-applied chemically-induced whitening of teeth in adults (Protocol). Cochrane Database of Systematic Reviews 2013, Issue 2. Art. No.: CD010379. DOI: 10.1002/14651858.CD010379.  aims to assess the effects of [read the full story…]

New Cochrane Protocols for December 2012


December brings two new protocols to the Cochrane Library from the Cochrane Oral Health Group. The first of these:-  Liu JLY, Walsh T, Kerr AR, Lingen M, Brocklehurst P, Ogden G, Warnakulasuriya S, Scully C. Diagnostic tests for oral cancer and potentially malignant disorders in patients presenting with clinically evident lesions (Protocol). Cochrane Database of [read the full story…]

New Cochrane Protocols for Oct and Nov 2012


October saw one new Cochrane protocol published on the Cochrane Library which slipped passed the Elf’s gaze. Cope A, Francis N, Wood F, Mann MK, Chestnutt IG. Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults (Protocol). Cochrane Database of Systematic Reviews 2012, Issue 10. Art. No.: CD010136. DOI: 10.1002/14651858.CD010136. The principal [read the full story…]

Weak evidence for honey in prevention of oral mucositis for cancer patients radiotherapy

shutterstock_49898071-MRI Scanner

Oral mucositis is a common side effect of  the treatment of malignancy with chemotherapy or radiotherapy. Two Cochrane reviews (see below) have looked more broadly at interventions for  prevention and treatment of this unpleasant side effect of treatment.  The aim of this review was to assess the protective effect of honey in head and neck [read the full story…]

New Cochrane Protocols

Logo of The Cochrane Collaboration

The November issue of the Cochrane Library sees  the publication a  number of new oral health related protocols. This indicates research in progress, of course, and we would not expect results to be published for some time.  However, people who are investigating these topic areas may like to know that a review is under way. [read the full story…]

Some evidence that early neck surgery reduces recurrence of the cancer

shutterstock_2092494 Dentist and assistant are examining you the patient

There were more than 404,000 new cases of oral cancers worldwide in 2002.  Oral cancer is  the are the sixth most common cancer worldwide, accounting for an estimated 4% of all cancers. Incidence and mortality varies geographically.  Surgery plays an important part of the management of oral cavity cancer with regard to both the removal [read the full story…]

Updated systematic review on surgery for oral cancer

An operating theatre.

The existing Cochrane systematic review on surgical treatment of oral and oropharyngeal cancers has been updated, with important changes to the conclusions. The reviewers concluded that  there was weak evidence to suggest that dissection of clinically negative neck nodes at the time of removal of the primary tumour reduced cancer recurrence.  However, there was insufficient [read the full story…]

Human papillomaviruses strongly associated with oral cancer

shutterstock_18549316- HPV virus

The role of human papillomaviruses (HPV) in the development of premalignant and oral squamous cell carcinoma (OSCC) is a hotly debated topic despite recognition of its role in cervical squamous cell carcinoma of uteri. The main aim of this systematic review was to calculate the pooled estimates of the odds ratio (OR) for the association [read the full story…]

Malignant transformation in patients with oral lichen planus


This cohort study of 327 oral lichen planus (OLP) patients; 229 women (70.0%) and 98 men (30.0%), was conducted using data from a cohort of caucasian patients from Italy with clinical and pathologic diagnosis of OLP, according to revised and modified World Health Organization diagnostic criteria. Follow-up of the patient cohort was started 6 months [read the full story…]

Malignant transformation rates in oral potentially malignant disorders


The aims of the study were to determine how frequently oral potentially malignant disorders (OPMDs) transform to cancer and to identify clinical and histological factors determining the rates of transformation. The study cohort  included 1357 patients with biopsy-confirmed OPMDs seen at Guy’s Hospital between 1990 and 1999 and followed up until 2005.  The patients’ details [read the full story…]