The existing Cochrane systematic review on surgical treatment of oral and oropharyngeal cancers has been updated, with important changes to the conclusions. The reviewers concluded that there was weak evidence to suggest that dissection of clinically negative neck nodes at the time of removal of the primary tumour reduced cancer recurrence. However, there was insufficient [read the full story…]
The role of human papillomaviruses (HPV) in the development of premalignant and oral squamous cell carcinoma (OSCC) is a hotly debated topic despite recognition of its role in cervical squamous cell carcinoma of uteri. The main aim of this systematic review was to calculate the pooled estimates of the odds ratio (OR) for the association [read the full story…]
This cohort study of 327 oral lichen planus (OLP) patients; 229 women (70.0%) and 98 men (30.0%), was conducted using data from a cohort of caucasian patients from Italy with clinical and pathologic diagnosis of OLP, according to revised and modified World Health Organization diagnostic criteria. Follow-up of the patient cohort was started 6 months [read the full story…]
The aims of the study were to determine how frequently oral potentially malignant disorders (OPMDs) transform to cancer and to identify clinical and histological factors determining the rates of transformation. The study cohort included 1357 patients with biopsy-confirmed OPMDs seen at Guy’s Hospital between 1990 and 1999 and followed up until 2005. The patients’ details [read the full story…]
This study examined the cost-effectiveness of a visual inspection for oral cancer prevention in individuals aged 35 years or older, in India. The authors concluded that oral cancer screening by visual inspection was cost-effective, particularly for a high-risk population. They reported that screening by visual inspection saved 269.31 life-years per 100,000 patients at a cost [read the full story…]
