Results: 1711

For: Treatment

Can a machine learning approach help us predict what specific treatments work best for individuals with depression?

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Marcus Munafo explores a recent study that uses a machine learning approach across two trials (STARD*D and CO-MED) to try and predict treatment outcomes (primarily focusing on the antidepressant citalopram) for depression.

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Is the NICE guideline for bipolar disorder biased in favour of psychosocial interventions?

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Guy Goodwin reviews a new paper in the Lancet Psychiatry by Jauhar, McKenna and Laws, that calls into question the trustworthiness of the NICE bipolar disorder guidance.

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Aripiprazole for treatment-resistant depression in older adults

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Sarsha Wilson publishes her debut blog about a recent RCT on the efficacy, safety and tolerability of augmentation pharmacotherapy with aripiprazole for treatment-resistant depression in later life.

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CBT plus medication for treatment-resistant depression: the CoBalT RCT long-term follow-up

In February 2016 we blogged CoBalT and concluded that CBT plus usual care (including antidepressants) is clinically and cost effective in the long-term for people whose depression has not responded to medication.

Sarah McDonald considers the findings of the CoBalT RCT long-term follow-up, which finds that CBT plus antidepressants are clinically and cost effective for treatment-resistant depression in primary care.

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A new MANTRA for treating anorexia nervosa? The MOSAIC study

Reflections

Helen Bould considers the findings of the MOSAIC RCT that compares the Maudsley Model of Anorexia Nervosa Treatment for Adults (MANTRA) with Specialist Supportive Clinical Management (SSCM) in outpatients with broadly defined Anorexia Nervosa.

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Group psychotherapies for schizophrenia

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Tracey Roberts appraises a systematic review of group psychotherapies for schizophrenia, which includes group CBT, music therapy, art therapy and social skills training.

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Omega-3 fatty acids for depression: Cochrane find insufficient evidence to support use

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Lisa Burscheidt summarises a recent Cochrane systematic review of Omega-3 fatty acids for depression in adults, which finds a lack of evidence to determine the effects of n-3PUFAs as a treatment for major depressive disorder.

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Lamotrigine, quetiapine and folic acid for bipolar depression: the CEQUEL trial

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Michael Ostacher considers the findings of the CEQUEL trial, which asks: Does lamotrigine treat bipolar depression when added to quetiapine, and does adding folic acid help any more?

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#SafeStaffing Mental health nursing on inpatient wards

We need validated assessments of depression.

John Baker looks at the implications of the leaked NICE review on #SafeStaffing for Nursing in Inpatient Mental Health Settings, which was recently uncovered by HSJ journalist Shaun Lintern.

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