Long-term care placement for people with dementia

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Clarissa Giebel reports on a systematic review and meta-analysis of factors predicting care placement of dementia sufferers into long-term care facilities.

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Cochrane find no evidence for as required PRN medication for mental health inpatients

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John Baker summarises an updated Cochrane review on ‘as required’ PRN medication regimens for seriously mentally ill people in hospital, which finds no randomised controlled trials that support this widely used intervention.

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Nalmefene for alcohol dependence: new evidence casts doubt over NICE recommendations

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Matt Field presents new evidence on the risks and benefits of nalmefene in the treatment of adult alcohol dependence, which casts further doubt over the controversial recommendations made by NICE and the European Medicines Agency.

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CBT and motivational interviewing: best bet for cannabis cessation? #CannabisMatters

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Mark Monaghan writes his debut Mental Elf blog about a systematic review on psychological and psychosocial interventions for cannabis cessation in adults. Part of our #CannabisMatters series, this review suggests that CBT and Motivational Interviewing may improve outcomes in a self-selected population of cannabis users.

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Psychosocial interventions for cannabis use disorder #CannabisMatters

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Ian Hamilton presents the findings of a recent Cochrane review, which finds that despite the large number of cannabis users seeking treatment, we still know relatively little about the best psychosocial interventions for cannabis use disorder.

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Music therapy for depression in older adults: How can I be sure of you?

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Dave Steele appraises a systematic review that reports music therapy combined with standard therapies is effective for treating depressive symptoms in older adults. He’s unconvinced by these claims and would like a bit more harmony in the evidence-base before striking up the band.

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Childhood maltreatment and bipolar disorder

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Emily Currell writes her debut Mental Elf blog about a recent Lancet Psychiatry systematic review, which reports that childhood maltreatment is associated with an unfavourable course of bipolar disorder in adult years.

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Treatment for depression in traumatic brain injury: Cochrane find no evidence for non-pharmacological interventions

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Eleanor Kennedy summarises a recent Cochrane systematic review, which finds no evidence to support the use of non-pharmacological interventions for depression in traumatic brain injury.

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Amphetamines and methylphenidate for paediatric ADHD: meta-analysis of n-of-1 trials

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Samuele Cortese publishes his debut Mental Elf blog on a meta-analysis of n-of-1 trials, which shows that amphetamine derivatives and methylphenidate are superior to placebo, in the short term, for paediatric ADHD.

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Pharmacotherapy for smoking cessation in severe mental illness

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Andrew Jones reports on a recent systematic review and network meta-analysis of the efficacy and tolerability of pharmacotherapy for smoking cessation in severe mental illness, which finds a promising but low quality result for bupropion and varenicline.

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