This update of a 2012 Cochrane review of the effectiveness of crowns or conventional fillings for root filled teeth found insufficient evidence to assess the effectiveness of either approach.
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Mark Smith presents the findings of a recent systematic review and meta analysis of therapeutic interventions for suicide and self-harm in young people.
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16 studies were included in this review but the majority were retrospective with only 1 RCT at unclear risk of bias. While the available data suggests satisfactory clinical outcomes, no high quality evidence is available.
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Another new review of local or systemic azithromycin as an adjunct in non-surgical periodontal therapy includes 14 RCTs and demonstrates small benefits in periodontal parameters. However, the included studies are small and it is unclear if the benefits are clinically important.
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This review of azithromycin as an adjunct to scaling and root planing for periodontal disease included 9 small RCTs. While some studies demonstrated some small improvements in periodontal parameters, there was no data to demonstrate superiority of azithromycin against the standard antibiotic combination of metronidazole and amoxicillin.
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This review looks at the benefits and harms of cavity lining. However, only 3 very low quality studies comparing calcium hydroxide lining in primary teeth were identified. Restoration without lining did not significantly affect the risk of failure.
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This review of cavity liners retrieved 14 trials (11 RCTs). The available evidence was limited but some liners seem more suitable to achieve sterile cavities or reduce bacterial numbers than others.
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This review of periodontal disease and weight identified 5 cohort studies finding a positive association between weight gain and new cases of periodontitis; RR= 1.13; (95% CI; 1.06–1.20).
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Stephen Wood ponders the reliability of a recent systematic review and meta-analysis, which suggests that childhood adversity is significantly linked to an elevated risk of psychotic symptom persistence.
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This review looks at the association between periodontitis and obesity. It included 13 studies (8 cohorts; 5 clinical trials) and suggests that overweight, obesity, and weight gain, may be a risk factors for developing periodontitis.
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