A group of UCL Masters Students summarise a recent network meta-analysis of drug treatment for generalised anxiety disorder, which finds that Venlafaxine, Pregabalin, Escitalopram and Duloxetine are all viable alternatives to Benzodiazepines.
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This review of predictors of tooth loss in patients with periodontitis undergoing treatment and receiving supportive care included 20 studies. Findings suggest older, non‐compliant patients, smokers, diabetics, those with IL‐1‐polymorphism, and teeth with bone loss, high probing pocket depths, mobility, as well as molars, especially with furcation involvement, are at higher risk of tooth loss.
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This review of the efficacy of different anti-plaque chemical agents in managing gingivitis included 32 RCTS of toothpastes and 19 of mouthrinses suggested greater benefits with some agents.
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This review of the effectiveness of autologous versus alloplastic bone for secondary alveolar bone grafting in patients with cleft lip and palate included 4 small RCTs suggesting no difference between the approaches.
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This review of atraumatic restorative treatment or conventional treatment for restoration of root caries lesions in older adults included 3 RCTs providing is insufficient data to clearly rule out whether differences between ART and CT exist.
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Jonathon Tomlinson considers his options as a GP supporting people with depression and complex needs, after reading a new systematic review and dose-response meta-analysis, which suggests that higher doses of antidepressants bring maximum side effects with only marginal gains.
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This Cochrane review of oral hygiene interventions for people with intellectual difficulties included 34 studies (19 RCTs, 15 non-randomised studies) find some interventions provided benefits but their clinical importance was unclear.
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8 small short term RCTs were included in this review of the effect of photobiomodulation (low-level laser therapy) on dental implant stability and success suggesting no differences
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This review assessing the prevalence of geographic tongue in psoriatic and non-psoriatic patients includded 11 cas-controlled studies. Meta-analysis showed that the odds of having geographic tongue in patients with psoriasis was higher OR = 3.53 (95%CI; 2.56-4.86).
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This review of the the effectiveness of different antibiotic protocols to prevent early dental implant failure includes 9 RCTs showing that antibiotics were protective against early implant failures.
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