Results: 1411

For: meta-analysis

Oral health self-care behaviours in people with a serious mental illness

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This review of the of oral health self-care behaviours in people with serious mental illness (SMI) included 33 studies. Most of the included studies (18) were cross-sectional and a mjority (20)were considered to be of weak design.

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Peer support in mental health: understanding the evidence base, current challenges, and future opportunities #ActiveIngredientsMH

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In their debut blog, Magenta Simmons and Ellie Brown summarise a recent review on peer support for adults with mental health challenges, and present early findings from their active ingredients review on peer support for youth anxiety and depression.

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Medication‐related osteonecrosis of the jaw and non-antiresorptive medications

osteonecrosis

This review of the association between non-antiresorptive medications and medication‐related osteonecrosis of the jaw (MRONJ) included 70 studies. A majority of the studies (77%) were case series and the quantity and quality of the evidence is low so the findings should be interpreted cautiously.

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Nano-hydroxyapatite for caries prevention

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This review of the efficacy of fluoride-free nano-hydroxyapatite agents (nHA) to enhance remineralisation or hamper demineralisation of enamel caries included 10 small studies. 5 studies were in-vivo and 5 in-situ but they were of short duration with 7 being at high risk of bias so provide very low certainty evidence. Additional high quality well reported studies are needed to assess nHA.

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Post endodontic pain: Is it affected by irrigation technique?

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This review of whether ultrasonic irrigation results in less postoperative root canal treatment pain than conventional irrigation included 6 RCTs. The suggests less pain with ultrasonic irrigation for the first 48 hours but no difference at 72 hours.

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Composite resin restorations in posterior teeth – incremental or bulk fill?

Composite filling

This review of the performance (retention/fracture) of bulk-fill and incremental filled composite restorations place in the posterior teeth of adult patients included 14 RCTs. Only 4 of the studies were at low risk of bias and while no difference was shown between the two approaches but the number of failures was small small.

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The efficacy of periodontal regenerative therapies, more challenges with network meta-analysis

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Mark-Steven Howe takes a detailed look at this review update and network meta-analyses of periodontal regenerative therapies. He highlights the inclusion of non-resorbable membrane studies that are no longer used.

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Psychological interventions for youth depression and anxiety can improve emotion regulation skills #ActiveIngredientsMH

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In her debut blog, Ariadna Albajara Saenz summarises a recent active ingredients review, which finds that psychological interventions for youth anxiety & depression can improve emotion regulation skills.

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Oral examination for detecting oral cancer

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This review of the diagnostic accuracy of visual inspection compared with biopsy (gold standard) for the diagnosis or oral cancer and oral potentially malignant dissorders included 18 studies. For malignant lesions the pooled sensitivity was 88% (95%CI; 73% to 95%) and specificity 81%(95%CI; 51% to 95%).

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Internal bleaching of endodontically treated discoloured teeth

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This review of different bleaching agents used for internal bleaching of endodontically treated discoloured teeth included 8 studies. While the findings suggest all agents had a positive effect the quality of the avaiiable studies is low so the findings should be interpreted cautiously.

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