Results: 1413

For: meta-analysis

Collaborative care for depression: psychological interventions, alone or in combination with medication, offer additional benefits

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Ioana Cristea reviews a recent systematic review and meta-analysis of collaborative care for depression, looking to identify factors predicting improvements. The study finds that collaborative care successfully improves both patient outcomes and the process of care for depression.

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Mandibular condylar fractures: is surgical or non-surgical approach best?

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Review of 36 studies at high risk of bias suggests that surgical treatment of mandibular condylar fractures provides a better clinical outcome for post-treatment malocclusion, protrusion, laterotrusion, and lateral deviation during maximal incisal opening in comparison to non-surgical treatment. But more patients affected by post-treatment infection.

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Cannabis and mania: what’s the link?

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Kathryn Walsh summarises a systematic review which finds that cannabis use may exacerbate symptoms of mania in those with a diagnosis of bipolar disorder, and trigger symptoms of mania in the general population.

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Long duration of untreated psychosis is associated with a range of poor outcomes

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Joe Judge appraises a recent systematic review and meta-analysis looking at the duration of untreated psychosis as a predictor of long-term outcomes in schizophrenia.

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Mental health anti-stigma programs are (broadly) successful

it is vital that such anti-stigma programs are informed by high quality research evidence

Dave Steele reports on a recent meta-analysis of mental health anti-stigma programs, which on the whole are found to be effective at reducing the stigma associated with mental disorders.

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Peri-implantitis: little evidence that particular non-surgical treatments are better than debridement alone

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This Bayesian network meta-analysis only included 11 small studies of overall low quality. While the greatest reduction in PPD was seen with debridement in conjunction with antibiotics the difference are small so it is difficult to conclude that any particular non-surgical treatment for peri-implantitis performs better than debridement alone

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Antidepressants for depression in pregnancy: new systematic review says the jury’s still out

Nikki Newhouse summarises a recent US health technology assessment of antidepressants for depression in pregnancy and the postpartum period, which concludes that the evidence remains inconclusive about the benefits and harms of antidepressants for depression in pregnancy.

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Chronic periodontitis: review suggests that Er:YAG laser may provide short term improvement

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This review compares the clinical outcomes of scaling and root planing with Er:YAG laser either as an alternative or as an adjuvant in patients with chronic periodontitis. 12 small trials were included and similar outcomes were seen with both treatments at 3 months . However hetrogeneity in teh studies and the small sample size mean that these finding should be interpreted with caution.

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Anterior mandibular fractures: review suggests lag screws and 1 plate plus an arch bar were superior to 2 miniplates for fixation

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This is one of a series of reviews that has looked at postoperative complications following different treatments for mandibular fractures. This review focuses on anterior mandibular fractures with the findings suggesting that lag screws and single miniplate plus an arch bar were superior to 2 miniplates

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Efficacy of high vs. low-potency first-generation antipsychotics for schizophrenia

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Laurence Palfreyman summarises 3 recent Cochrane reviews, which investigate high-potency versus low-potency first-generation antipsychotic drugs for schizophrenia. The reviews find little difference in efficacy between the high-potency antipsychotics Trifluoperazine, Haloperidol, Fluphenazine, and low-potency typical antipsychotics.

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