Dan-Mikael Ellingsen explores the neurochemistry of placebo effects in major depression, as he reviews a recent study of the association between placebo-activated neural systems and antidepressant responses.
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Michael Ostacher provides some context and ideas for the JoinMQ conference on research priorities for bipolar disorder, which is taking place in London on 9-10 November 2015.
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Tracey Roberts summarises a recent diagnostic test review, which suggests that early improvement can act as a predictor of later response to antipsychotics in schizophrenia.
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Clarissa Giebel summarises a recent systematic review that investigates the effectiveness of various psychotherapies (CBT, interpersonal therapy, counselling) for depression and anxiety in people with dementia or mild cognitive impairment.
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Simon Wessely responds to the huge amount of recent criticism that has surrounded the publication of a follow-up paper of the PACE trial into chronic fatigue syndrome. This extended blog presents the PACE trial and its main results, but also reminds us what makes a good RCT, as well as exploring how well PACE measures up.
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Rachel Brand looks at a recent RCT which investigates the optimal duration of an early intervention in psychosis programme for young people in Hong Kong.
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This new systematic review explored the links between eating disorders and oral health, which were first noted in the 1970s. Ten studies were included in the review and higher odds of dental erosion were seen in those with eating disorders, with the odds being greater in those with self-induced vomiting.
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David Steele talks us through a systematic review and meta-analysis, which found that commonly used interventions are effective at preventing completed suicides at suicide hotspots.
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Lisa Burscheidt appraises an RCT of telemedicine psychotherapy for depression in older veterans, which establishes non-inferiority of telemedicine delivery versus same-room delivery of behavioural activation.
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Sarah McDonald considers surely one of the most difficult of questions: should assisted dying be available to people with treatment resistant depression?
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