Why do people who were maltreated as children face higher risks of both mental and physical illness? A new Mendelian randomisation study suggests that metabolic markers — like triglycerides and blood sugar — may be part of the chain connecting adversity to later multimorbidity.
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What works better for young people with depression: therapy or medication? This new analysis shows why the trials may be too different to compare, and why value-based decisions matter more than ever.
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With classroom mental health programmes on the rise, this review raises an important question: are we doing more harm than good? The evidence suggests universal interventions may not be right for everyone.
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Natural disasters often trigger serious mental health problems, but can these be prevented? This new meta-analysis tested psychological and psychosocial interventions aimed at survivors and first responders, and the results may surprise you.
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Can a nurse-led, digital mental health intervention for common mental disorders reduce sick leave and save money? This RCT from Sweden looked at cost, care, and what matters to patients.
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Dona Mathews highlights a new study showing a doubled risk of depression after a medical diagnosis – especially in the first month post-diagnosis, for those who are hospitalised for their medical condition, those with multiple medical conditions, those over 60, and for women.
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Inflammation is a key factor in depression for many people. This new RCT used an experimental immune challenge to explore how individuals with high inflammation respond differently—shedding light on a distinct biological subtype of depression.
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GLP1 drugs are already used to treat diabetes and support weight loss, but do they have any impact on mental health? This new meta-analysis looks at the evidence from 80 clinical trials.
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Despite strong evidence, collaborative care remains underused in the NHS. This blog explores new findings that highlight which components of the model are most effective in reducing depression symptoms.
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CBT is a cornerstone of mental health care, but how well does it really work across different disorders? This massive new meta-analysis offers some answers and raises new questions.
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