This review of the use and diagnostic accuracy of saliva tests for the detection of SARS-CoV-2 included 16 studies. THe findings suggests good diagnostic accuracy but furteher research is needed to determine confounding factors such as method and time of sample collection, transport medium, storage etc. prior to population testing.
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This review evaluating the worldwide prevalence and epidemiology profile of burning mouth syndrome included 18 studies. Population based studies suggest an overall prevalence of 1.73% and clinically-based studies a 7.72% prevalence.
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This review of the influence of different regenerative techniques and materials on the outcome of endodontic surgery includes 11 RCTs. The findings suggest that regenerative approaches improve periapical lesion healing after endodontic surgery. However the studies are small and only 2 are at low risk of bias.
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In her debut blog, KCL student Melisa Eyuboglu summarises a meta-synthesis, which investigates the CATCH model (Commitment, Advocacy, Trust, Collaboration and Health) for addressing domestic violence and abuse.
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In her debut blog, Sophie Large appraises a recent Campbell systematic review exploring the impact of care farms on quality of life, depression and anxiety among different population groups.
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This review of the effect of probiotics on gingival inflammation and oral microbiota in patients suffering from plaque-induced gingivitis included 11 RCTs. No clear evidence was found to indicate that oral probiotics have a positive effect on gingival inflammation and oral microecological environment of patients with gingivitis.
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This update of an earlier review of the malignant transformation rate of oral leukoplakia included 24 retrospective studies. The pooled proportion of malignant transformation was 9.8% (95%CI; 7.9 to 11.7%)
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Andrew Sommerlad appraises a recent review on the efficacy of interventions for depression in people with dementia, which identified several non-drug treatments that can have a meaningful effect on depressive symptoms in dementia.
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In her debut blog, Suzi Sapiets summarises a review exploring psychological treatment of depression in young people with neurodevelopmental conditions, which finds very limited evidence to help neurodiverse individuals. She also tells us that it’s time to #EmbraceComplexity and encourages people to join the Embracing Complexity Research Network.
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This review of systemic or locally delivered clarithromycin as an adjunct to non-surgical periodontal therapy included 7 small RCTs, 4 RCTS related to systemic use and 3RCTS for local application. The findings provide moderate certainty evidence suggesting locally delivered clarithromycin significantly improves treatment outcome
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