Results: 675

For: randomised controlled trial

Amoxycillin not helpful for acute sinusitis

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Acute sinusitis (rhinosinusitis) is a common disease with 1 in 5 antibiotic prescriptions for adults in the United States being for sinusitis.  US Centers for Disease Control  and Prevention (CDC) guidelines recommend using clinical criteria for diagnosis and  reserving antibiotic treatment for patients with moderately severe or severe symptoms.  The aim of this study was [read the full story…]

4% articaine and 2% lidocaine with epinephrine have similar effectiveness in achieving anaesthesia in maxillary teeth

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The aim of the study was to compare the anaesthetic efficacy of buccal infiltrations of 4% articaine with epinephrine (1:100,000) and 2% lidocaine with epinephrine (1:80,000) in achieving anaesthesia in maxillary permanent teeth with irreversible pulpitis. Patients aged 16 years and over who presenting with irreversible pulpitis in one tooth and an asymptomatic vital tooth [read the full story…]

Physical therapy did not have an additional effect over advice on management of patients with temporomandibular disorders

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Physical therapy (PT) is recognised as a conservative method for the management of temporomandibular disorders (TMD). However, some studies suggest that physical therapy provides minimal, if any therapeutic effect while others suggest evidence to support its use for the treatment of TMD.  The aim of this trial was to investigate the effect of physical therapy [read the full story…]

Good success rates in pulpotomy of immature caries-exposed permanent molars

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The aim of this study was to  compare the  outcomes of pulpotomy treatment using calcium-enriched mixture (CEM) cement and mineral trioxide aggregate (MTA) in carious-exposed vital immature permanent first molars. Participants (n=51,  1 tooth per patient)  with immature molars with clinical carious exposure with symptomatic/asymptomatic pulpitis were randomised to  undergo pulpotomy using either CEM (n=26) [read the full story…]

Trial suggests no difference at 3 years in failure rates between implants that were loaded immediately or early

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The traditional approach to placing dental implants was to submerge them and keep them load-free for 3–8 months to minimize the risk of implant failures.  During the healing phase temporary prosthesis are often used and patients can find these uncomfortable. Consequently shorter healing periods without jeopardizing implant success would be beneficial.   Nowadays immediate and early [read the full story…]

Custom-made mouthguards had no detrimental effect on athletic strength and performance

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The use of mouthguards are important for the prevention of dental and maxillofacial injuries when participating in contact support. Mouthguards buffer the impacts or blows that might otherwise cause moderate to severe dental and maxillofacial injuries. Mouthguards were recommended by the American Dental Association in 1950. However, while they have been shown to reduce injury [read the full story…]

Implant overdentures do not have a more positive effect on the nutritional state of elderly at 12 months

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As teeth are lost masticatory efficiency declines and this may have a negative impact on diet which may be of particular relevance in older people.  The aim of this trial  was to assess the effects of mandibular  implant overdentures (IODs) on the nutritional status of an edentate elderly population. Participants were randomized to  receive  either  [read the full story…]

Web portal helps paediatricians adhere to ADHD guidelines, according to randomised controlled trial

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Mental health is an area where a lot of evidence-based guidelines now exist. A lack of evidence isn’t always the problem. In some cases, one of the key issues is that clinicians don’t adhere to the guidelines. The reasons for this can be many and varied: because they don’t know about the guidelines, because it’s [read the full story…]

Better outcomes with metronidazole and amoxicillin as an adjunct to full mouth disinfection for patients with aggressive periodontitis

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About 1 in 1000 susceptible patients suffers from aggressive periodontitis. Sufferers have more rapid  gingival attachment loss with some losing more that half their bony support by 35. This can be localised  to a small number of teeth or more generalised.  The aim of this study was to evaluate the adjunctive clinical and microbiological effects [read the full story…]

Promising results from minimal intervention approach to proximal caries in young adults.

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There is increasing interest in non-surgical approaches to the management of dental caries to preserve tooth structure.  The aim of this study was to compare the effect of infiltrating vs. sealing proximal caries lesions against placebo after 3 years. The study was a split mouth design conducted in young adults in Colombia.  Individuals with 3 [read the full story…]