Results: 675

For: randomised controlled trial

Hall technique for managing carious primary molars shows good long term outcomes.

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There is a growing literature supporting caries management options where caries is sealed in beneath restorations or sealants. The aim of this trial to compare long-term (at 5 yrs) outcomes for carious primary molars managed by GDPs’ standard conventional restorative methods (control) with the Hall Technique in general dental practice.   The outcomes at 2 years [read the full story…]

Including people with learning disabilities as researchers and participants in RCTs is possible

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There are specific difficulties in developing an evidence base for practice in supporting people with learning disabilities. There is general agreement that some degree of sprcialist services are required, but little agreement about the nature of these services or the best method of their delivery. It may be possible to transfer ideas directly from mental [read the full story…]

New RCT suggests memantine is not an effective treatment for dementia in people with Down syndrome

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Our colleagues at the Mental Elf  found this small randomised controlled trial looking at the use of memantine for people with Down syndrome and dementia. The trial is being reported in the Lancet. People with Down’s syndrome are more likely to develop dementia than others and one in three will have the illness as early [read the full story…]

Optimal oral dose of midazolam for the anxious child requiring dental treatment is 0.75 mg/kg

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Behavioural management is an essential approach for the dental treatment of the anxious child.  It is sometimes  necessary to supplement this with sedation.  The main aim of this study was to compare the effect of three doses of oral midazolam (0.5, 0.75, and 1 mg ⁄ kg) on the sedative state and cooperative behaviour of  [read the full story…]

More psychotherapy does not improve social functioning for depressed people also taking antidepressants

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This is an unusual randomised controlled trial conducted by a research team from Arkin Institute for Mental Health in Amsterdam and funded by Eli Lilly. The study measures social functioning as an outcome, as well as the more commonly measured depression symptoms. It aims to find out how much psychotherapy is optimal for depressed people [read the full story…]

Smear layer removal improved pulpectomy outcome in primary teeth

Photograph of carious teeth

Pulpectomy is, indicated for primary teeth with irreversibly inflamed or necrotic radicular pulps because of caries or trauma. The main aim of this trial was to evaluate the outcome of pulpectomy with smear layer removal versus no smear layer removal. Patients were randomised to receive pulpectomy under rubber dam with either smear layer removal (G1) [read the full story…]

Adding CBT to drug therapy helps children with OCD who don’t respond to antidepressants alone

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Obsessive compulsive disorder (OCD) is a condition that is usually associated with obsessive thoughts and compulsive behaviour. It’s one of the most common mental health problems in young people, with an estimated 5% of children and teenagers suffering from the chronic condition. Studies have shown that SSRI antidepressants and cognitive behavioural therapy (CBT) are both [read the full story…]

Calcium hydroxide effective for partial pulpectomy in primary molars

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Pulpotomy  is one of a number of approaches (indirect pulp capping, direct pulp capping, pulpotomy, pulpectomy) for managing carious lesions approaching the pulp of primary teeth with the aim of retaining  the tooth in a symptom free state until it is lost naturally thus avoiding an extraction.  Formocresol has been used for a number of [read the full story…]

Trauma-focused cognitive behavioural therapy may help young children with post traumatic stress disorder

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Recent studies have shown that pre-school children can be affected by post traumatic stress disorder (PTSD) and that the condition can last for years even after treatment. Good quality randomised trials have shown that trauma-focused cognitive behavioural therapy can be a very effective treatment for older children and adolescents with PTSD, but there have been [read the full story…]

Chlorhexidine is not effective in preventing coronal caries

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While dental caries has a significant impact on adults much of the research on the prevention of this common disease is focussed on children.  The aim of this study was to test the hypothesis that a chlorhexidine (CHX) coating, compared with a placebo coating, reduces dental caries increment in at-risk adults over a period of [read the full story…]