Results: 675

For: randomised controlled trial

Tranexamic acid is effective in controlling blood loss in orthognathic surgery

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Conservation of blood is important in all forms of surgery and approximately 30% of patietns undergoing bimaxillary osteotomies require a transfusion. The aim of this trial was to assess the effect of tranexamic acid on blood loss, quality of surgical field and duration of surgery compared to the effect of nitroglycerin induced moderate hypotension alone [read the full story…]

Text messaging may improve oral health knowledge, attitudes and practices

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The aim of this study was to compare the effectiveness of delivery oral health messages by text messages and pamphlets to mothers of pre-school children. The study was conducted in India and restricted to mothers with mobile phones who could speak English. Mothers were randomised to received 3 text messages per day ( text message [read the full story…]

Web-based CBT is equal to face-to-face CBT at reducing anxiety in adolescents, accordingly to randomised controlled trial

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I’ve blogged about computerised cognitive behavioural therapy (CCBT) a few times over recent months and highlighted research that shows it is effective in treating a range of mental health conditions. Research shows that most young people do not seek treatment for anxiety problems. There are lots of good quality reviews and trials that support the [read the full story…]

Glass fibre-reinforced posts performed better at 5 years in endodontically treated teeth

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Post systems are used in the restoration of endodontically treated teeth where there has been significant loss of the clinical crown. A post provides a method to secure filing material to the tooth.  The aim of this trial was to  assess the survival rate of two different post systems after 5 years of service. Patients [read the full story…]

Group art therapy does no better than standard care at improving symptoms for people with schizophrenia

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People with schizophrenia experience a wide range of symptoms, which are broadly categorised into ‘positive’ symptoms (e.g. hallucinations and delusions) and ‘negative’ symptoms (e.g. lethargy, lack of motivation and poor attention). Evidence shows that positive symptoms can be well managed with antipsychotic drugs, which also reduce the chances of relapse, but these medications can have [read the full story…]

Online CBT is an effective treatment for chronic fatigue syndrome in adolescents, according to small RCT

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Existing trials have shown that cognitive behavioural therapy is a promising treatment for chronic fatigue syndrome. The availability of CBT is patchy, so there is an increasing body of research investigating whether internet-based treatment is a viable alternative. A new small randomised controlled trial conducted by researchers from the Netherlands has been published in the [read the full story…]

Good pulpotomy success rates in permanent molars with calcium enriched mixture cement or mineral trioxide aggregate

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This large clinical trial compares the outcomes using two materials for pulpotomies in permanent teeth demonstrating good success at 12 months.

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Periodontal treatment may improve metabolic control in diabetic patients.

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There have been a number of studies including a recent Cochrane review which have looked at the impact of periodontal treatment on glycaemic control in diabetics. The aim of this study was to investigate the effects of nonsurgical periodontal therapy on metabolic control in Type 2 diabetes mellitus (DM2) Forty patients with DM2 and chronic [read the full story…]

Adding mannitol improved the effectiveness of local anaesthesia

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Modern local anaesthetics have transformed the practice of dentistry. However  a proportion of  injections fail to achieve pulpal anaesthesia.   This trial set out to find if  the addition of mannitol to lidocaine with epinephrine improved its efficacy. Forty patients were randomised to receive  an inferior alveolar nerve (IAN) block  in 3 separate appointments spaced at [read the full story…]

How to speak to your psychiatrist: are we ready for shared decision making in mental health?

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There’s a lot of talk about ‘shared decision making’ in the NHS right now. Many mental health patients say that they do not feel that they are properly listened to or that their expertise is not valued in the consultation, but it’s clear that many health professionals are quite evangelical about working in partnership with [read the full story…]