Results: 675

For: randomised controlled trial

Similar performance from glass fibre–reinforced epoxy resin posts and titanium posts in endodontically treated teeth at 7 years

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Yesterday (Dental Elf 14th Jan 2012) we looked at a review that compared cast and fibre posts in-vitro. Here we are looking at a trail that compares the use of more flexible, dentine-like (low Young modulus) glass fibre–reinforced epoxy resin posts (GFREPs) with rather rigid, stiff (higher Young modulus) titanium posts (TPs) in order to [read the full story…]

Study shows that berberine had a positive effect on recurrent aphthous ulceration

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Recurrent aphthous stomatitis (RAS) is usually episodic and self-limiting but can produce severe ulcers that interfere with eating speaking and swallowing.  Minor RAS  (MiRAS) is the most common form.  The aim of this trial was to investigate the efficacy and safety of berberine (an isoquinoline alkaloid originally isolated from medicinal herbs) in the treatment of [read the full story…]

Small study shows improvements in obstructive sleep apnoea/hypopnoea syndrome with two designs of oral appliance

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Obstructive sleep apnoea/hypopnoea syndrome (OSAHS) is though to affect around 4% of the male and 2% of the female population of North America. Continuous positive airway pressure (CPAP) particularly for moderate to severe cases.   The aim of this cross-over trial was to compare the two types of mandibular advancement appliances (MAAs) with different structures, retention [read the full story…]

Short term exercise programme improves muscle strength and agility in adolescents with Down syndrome

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The benefits of exercise for a healthy lifestyle are now well understood. However, there are issues relating to the physiology of people with Down syndrome which might suggest limitations to the extent to which they can engage in cardiovascular or resistance exercises. we also know that many people with Down syndrome are overweight or obese. [read the full story…]

New RCT shows that adding CBT to usual care helps people with treatment resistant depression

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The CoBalT trial was published last week in the Lancet. This important randomised controlled trial (RCT) examined the effectiveness of cognitive behavioural therapy (CBT) as an add-on treatment to usual care for people with treatment resistant depression. Previous studies have shown that only around one third of people with depression respond well to treatment with [read the full story…]

Trail suggests no difference in food choices and nutrient intake in older adults with conventional denture or implant-retained overdentures

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Evidence suggests that dietary intake and nutritional status of complete denture wearers is poorer than dentate patients of similar age, and implant retained dentures are considered to improve the retention and stability of complete dentures. The aim of this study was to compare dietary intake in edentulous adults with conventional dentures compared with implant-retained dentures. [read the full story…]

Borderline personality disorder improves with dialectical behaviour therapy and general psychiatric management

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Talking treatments are a key component of the therapy offered to people with borderline personality disorder and there are now a number of studies that point to the importance of these interventions for this complex and hard to manage condition. A new randomised controlled trial conducted by a research team from the Centre for Addiction [read the full story…]

Two endodontic irrigation protocols show similar effect on bacterial contamination during root canal treatment

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Elimination of bacteria from the root canal is a key aim of root canal treatment (RoCT). The aim of this study was to compare the results of a non-activated single-irrigation protocol (NAI) that used only 1% Sodium hypochlorite (NaOCl) with a passive ultrasonic multi-irrigation protocol (PUI) that used 1% NaOCl, 17% ethylenediaminetetraacetic acid (EDTA), and [read the full story…]

Small study finds limited benefit for lavage to supplement local anesthetic treatment for treatment of temporomandibular disorders

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It has been estimates that 20% to 30% of the adult population will experience temporomandibular joint dysfunction. The aim of this study was to assess the short-term efficacy of two treatments for patients with permanently displaced discs and temporomandibular disorder (TMD) pain. Adult patients( ≥ 18)  with TMD  pain and disk displacement without reduction (DDwoR)  [read the full story…]

Teaching GPs about depression and suicide can help reduce the risk of suicide in depressed older adults, says new RCT

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A great deal of time and money has been spent on improving the diagnosis and management of depression and self-harm in primary care. The evidence tells us that collaborative care and case management can be effective approaches, which is all well and good, but these complex interventions are not always feasible. This new cluster randomised [read the full story…]