Results: 675

For: randomised controlled trial

NICE publish evidence update on generalised anxiety disorder in adults

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NHS Evidence have published an evidence update on generalised anxiety disorder in adults. Evidence updates are summaries of selected high quality evidence that has appeared since the relevant guideline was published, in this case NICE clinical guideline 113 ‘Generalised anxiety disorder and panic disorder (with or without agoraphobia) in adults: management in primary, secondary and community care’ [read the full story…]

Some toothpastes have some impact on mouth bacteria in short term

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There is good evidence that toothbrushing reduces gingivitis and that tooth brushing with fluoride toothpaste reduces tooth decay. The aim of this study was to compare the antimicrobial effects of three commercially available toothpastes. Thirty-five adults (15 men and 20 women; average age 33 years and pockets <5 mm with a minimum of 20 natural [read the full story…]

New BMJ RCT finds that preventing depression in adolescents, with classroom-based CBT, may do more harm than good

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The prevalence of depression goes up sharply in mid-adolescence and it’s estimated that by age 19 up to 20% of people will have suffered from at least one episode of clinical depression. So it makes sense that prevention programmes should be targeted at young people in schools, and indeed, published research has shown that classroom-based [read the full story…]

Professional oral hygiene interventions and follow-up support provided short term improvement in oral health for in older adults

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An increasingly elderly population  have benefited from improvements in oral health care resulting in the retention of an increasing number of natural teeth. This brings the challenge of maintaining these  teeth and their replacements in good disease free condition.  However, studies indicate that oral health in this group is often poor.  The aim of this [read the full story…]

New RCT reports a promising primary care solution to diagnosing and managing postnatal depression

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Postnatal (or postpartum) depression is moderate to severe depression that affects women just after they have given birth. It’s a relatively common illness, affecting 7-15% of childbearing women. Suffering from depression in the first few weeks of motherhood can have a significant impact, not just on the health of the mother, but also on her [read the full story…]

Should we be offering mindfulness-based cognitive therapy to all patients with residual depressive symptoms?

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Mindfulness-based cognitive therapy (MBCT) is a group training approach that aims to prevent relapse and recurrence of depression. It combines mindfulness techniques with cognitive therapy and research shows that it is effective at reducing depressive symptoms as well as preventing relapse. The NICE depression guideline recommends that MBCT is offered to people who have experienced [read the full story…]

Bupivacaine may reduce post-operative pain in patients having single visit root canal treatment

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Elimination of pain during and after root canal treatment is an important element of patient care and modern endodontic practice.  The aim of this study was to compare the postoperative pain and analgesic use after single-visit root canal treatment of acute irreversible pulpitis with either bupivacaine (a long-acting anaesthetic) or lidocaine. Patients with a first [read the full story…]

Community-based outreach may reduce mental health problems in women who experience intimate partner abuse

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Women who experience intimate partner abuse (IPA) often suffer from mental health problems as a result. Post-traumatic stress disorder (PTSD), depression and fear of further attacks are all common and understandable responses. Despite this, there are not many longitudinal studies that follow a group of women over a period of time and assess what interventions [read the full story…]

MoodGym no better than informational websites, according to new workplace RCT

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In these times of austerity, there is a lot of interest in computerised cognitive behavioural therapy (cCBT) as a treatment for people with depression and anxiety. It is hoped that this cheap and easy to deliver intervention can help to reduce the long waiting lists for face-to-face talking treatments. I’ve regularly blogged about cCBT over [read the full story…]

Maternal counselling using a motivational-interviewing approach reduced caries in indigenous children

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The aim of this trial was to test the use of motivational interviewing (MI) as an approach to control caries in indigenous children. This cluster-randomised trial was conducted in Cree communities in Quebec. Cree women who recently had given birth or were between the 12th and 34th weeks of pregnancy were recruited. Mothers allocated to [read the full story…]