Results: 675

For: randomised controlled trial

Shortened dental arch: trial suggests it improves quality of life more than conventional treatment using removable partial dentures

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This study suggests that treatment based on SDA concept led to better quality of life compared with treatment based on RPDs up to 12 months after treatment.

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Sustained smoking cessation intervention for hospitalised smokers

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Sally Adams summarises a new randomised controlled trial in JAMA, which tests a sustained care intervention and post-discharge smoking cessation for hospitalised smokers.

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Mandibular advancement devices: Trial suggests they can benefit patients with mild obstructive sleep apnoea-hypopnoea

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Obstructive sleep apnoea-hypopnoea (OSAH) affects 2-7% of adults. This trial compared 3 mandibular advancement devices with no treatment for mild disease and found benefits over the short term for a range of outcomes including Apnoea-Hypopnoea Index, the Epworth Sleepiness Scale and cost-effectiveness.

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Improving mental health literacy in the classroom: new HeadStrong RCT

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Lisa Burscheidt reports on an RCT of the Headspace mental health literacy intervention and the impact it has on the mental health literacy, stigma, help-seeking and mental health of a group of young people in Australia.

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Lidocaine: trial suggests that buffering may not improve success of inferior alveolar nerve block

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A 2010 Cochrane review that was not able to include any dental studies did find that buffering lidocaine decreased pain on injection and augmented patient comfort and satisfaction. This new dental trial included 80 patients with symptomatic irreversible pulpitis but found no significant difference with success rates with buffered lidocaine.

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Mouthrinses: trial finds alcohol-free rinses have similar effects on plaque levels to those containing alcohol

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This equivalence trial compared two alcohol free mouthrinses with an alcohol containing rinse and toothbrushing alone. At 8 weeks all 4 interventions reduced interproximal bleeding with plaque reductions being significantly greater in the mouthrinse groups. There was more staining in the 3 mouthrinse groups.

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Direct pulp capping: trial finds good short-term outcome success rate for new material in permanent teeth

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This small study found good short term success rates for a new MTA derived pulp capping material in permanent teeth. Larger well-conducted longer-term studies are necessary to establish its clinical utility.

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Plaque control during orthodontic treatment: study suggests that text messaging may have a positive effect

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This small study in orthodontic patients suggests that text messaging might improve plaque control in short term. Larger better quality studies are needed to provide more definitive answers.

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Depression and cancer: Lancet papers on prevalence and integrated collaborative care

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Kirsten Lawson highlights a trio of Lancet papers on the prevalence of depression in cancer patients and the efficacy of a new treatment programme called ‘Depression Care for People with Cancer’.

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Collaborative care for adolescent depression: new RCT shows promise

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Jennifer Laidlaw writes her debut blog on a recent RCT in JAMA about collaborative care for adolescent depression in primary care. The trial concludes that collaborative care is both feasible and effective in improving outcomes, but Jennifer highlights a number of limitations and questions for future research.

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