In this small trial the use of either an 8% arginine desensitising paste or prophy paste reduced dentine hypersensitivity after scaling but the arginine base paste was significantly better than the standard prophy paste.
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This well conducted trial found that there was no statistical difference if orthodontic brackets were bonded with or without the use of a primer after 12 months observation.
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Claire Mokrysz reports on two RCTs in JAMA that find no superiority over control for brief interventions for substance misuse in primary care. A finding that casts some doubt on interventions such as motivational interviewing for unhealthy drug use in primary care patients.
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The paper reports the finding of a small trial of three type of orthodontic retention 5 years or more post retention and finds no difference. Previously the authors reported their findings after two years of retention again showing no differences.
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Susie Johnson reports on the FolATED RCT and economic evaluation of folic acid for depression. The study finds no evidence that folic acid is clinically effective or cost-effective in augmenting antidepressants and speculates instead that methylfolate may be a better candidate for future research.
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Mindfulness is increasingly recognised as an effective way to reduce stress and improve well-being
Here Kate van Dooren looks at a randomised controlled trial of a mindfulness based stress reduction programme with mothers of children with autism and other developmental delays to look at its impact on levels of distress over time.
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Martin Webber looks at a rare social work randomised controlled trial (RCT) on relationship training for practitioners working with children and families and finds that even findings from a study using ‘gold standard’ research methodology have to be carefully examined for reliability.
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This well conducted and reported trial found that there was no difference between 3% mepivacaine & 2% lidocaine with 1:100,000 epinephrine and 2 cartridges of 2% lidocaine with 1:100,000 epinephrine in terms of injection pain, onset time, and pulpal anesthetic success for the IAN block.
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In her latest blog, Clarissa Giebel examines research into the effectiveness of the ‘Strategies for Relatives’ psychological and educational training programme for family carers of people with dementia and explores what the findings might mean for wider programme implementation.
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Elly O’Brien summarises a recent RCT of folic acid for depression, which explores whether mood disorders can be prevented in young people at familial risk. The trial finds no evidence that folic acid supplementation reduces the incidence of mood disorders compared to those taking placebo.
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