Results: 1711

For: Treatment

Largest RCT so far suggests that ketamine may be useful in the acute treatment of refractory depression

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Major depression is a serious mental illness that often does not respond to mainstream drug treatment (antidepressants). In addition, there is usually a delay of 2-6 weeks before mood improves significantly. In situations like this, when at least two conventional antidepressants have been tried without success, depression is considered treatment-resistant. While multiple different strategies to [read the full story…]

Digital innovation works best when users are involved at every stage

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Digital mental health is thriving in 2013 and we are thrilled to be part of the growing community with our Mental Elf website and app. We have had time to reflect on the development of the Mental Elf website recently, as André was interviewed by Hannah Nicklin from Hide and Seek who had been asked to [read the full story…]

Systematic review highlights a lack of evidence about using antidepressants to treat cancer patients with depression

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Having a life threatening disease such as cancer and undergoing gruelling treatment can have detrimental psychological effects. According to a recent review, for instance, the prevalence of depression among cancer patients is 10.8%, when assessed by a standardised clinical assessment (Ng et al. 2011). The authors of this meta-analysis make the argument that established criteria [read the full story…]

Exercise may help older people with dementia, but more research is needed

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Many of our older readers will remember tales of the Great Elf Mother running miles every day, o’er hills and vales, to bring the very latest evidence-based research to us younger elves at the breakfast table. It was she who inspired our National Elf Service, and I’m delighted to say that she’s still going strong [read the full story…]

New Cochrane review finds weak evidence that drug combinations are more effective than monotherapy in psychotic depression

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Major depression remains a serious condition that often proves refractory to pharmacological or psychotherapeutic interventions. Because depression can have many “faces”, clinicians should be aware of the great symptom variability among depressed patients and consider subforms when prescribing medication.  In a sizeable amount of patients (up to 25%, Coryell et al., 1984), depression presents with [read the full story…]

Self-report tool shows women with learning disabilities identify higher levels of symptoms relating to mood and self esteem

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Evidence suggests there is a greater prevalence of mental ill-health in people with learning disabilities, although the extent of this difference varies from study to study. At present there has been little work enabling people with learning disabilities to recognise potential threats to their mental health and to help with the development of strategies to [read the full story…]

Rapid generation of evidence for interventions in mental health of people with learning disabilities needed

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A couple of months ago, we posted about a trial of group based cognitive therapy to help with anger management in people with learning disabilities. The study was interesting in that it showed the approach was effective in improving anger control and in decreasing supporter rated challenging behaviour. What was also interesting about the trial [read the full story…]

Multisystemic therapy may help prevent adolescent sexual offenders from reoffending

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The sexual abuse of children is a worldwide problem that has lasting and sometimes lifelong impacts on the child, their family and the community. There is a substantial amount of research that now demonstrates the long term impacts of child sexual abuse which includes: The increased incidence of all types of mental health difficulties; Increased [read the full story…]

Is ‘natural’ better? Evidence for the efficacy of complementary therapies for antenatal depression

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Can we encourage patients to continue taking complementary and alternative (CAM) treatments for antenatal depression or should we be firmly discouraging them from doing so? We already know from surveys that 11% of primary care patients with anxiety and depression are taking complementary or alternative therapies, which is around the same proportion of people who [read the full story…]

Cochrane review finds no clear evidence for psychosocial interventions to help people with both severe mental illness and substance misuse

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Substance use is common in people with mental health problems, and this can have important negative consequences for health and social function. The high comorbidity of mental health problems and substance use is a major contributor to the shorter life expectancy of this population – a person with a severe mental disorder can expect to [read the full story…]