Dementia risk factors in people with mild cognitive impairment

People with a learning disability and family carers are able to talk about end-of-life care and healthcare professionals need to acknowledge and respect this expertise

Akshay Nair summarises a recent systematic review and meta-analysis of modifiable predictors of dementia in mild cognitive impairment. The meta-analysis finds that diabetes and the presence of any neuropsychiatric symptoms significantly predicted the conversion of mild cognitive impairment to dementia.

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Does exercise improve pain and function for osteoarthritis of the knee?

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We learnt in an earlier post about the burden of musculoskeletal conditions that osteoarthritis (OA) develops around the age of 50. Blimey some of our elves are approaching that age. What can we do to help any symptoms that start to develop? We eleves are always looking to stay fit and thought that exercise might help. But [read the full story…]

Varenicline and the risk of neuropsychiatric adverse events and death

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Natasha Clarke publishes her debut Mental Elf blog about a new systematic review and meta-analysis investigating the risk of neuropsychiatric adverse events associated with the smoking cessation drug varenicline.

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A multitude of systematic reviews on dementia diagnosis

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Clarissa Giebel highlights 5 new Cochrane reviews on dementia diagnosis, focusing on the Mini-Cog, IQCODE and MMSE diagnostic tests.

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Intermediate Care pathways for musculoskeletal conditions – are they working?

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In this blog, Lesley Dawson considers a systematic review examining musculoskeletal Intermediate Care pathways to evaluate their effectiveness, outcomes and identify gaps in evidence.

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Can self-injurious behaviour be reduced by medication in individuals with intellectual disabilities?

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Self injurious behaviour in people with learning disabilities, as well as causing physical harm, can have a major impact on quality of life. It is not entirely clear why people engage in self injurious behaviours, but one theory suggests that it may be connected with an opiate euphoria. If this is so, it might be that medications that blocked these opiates might impact on levels of SIB.

Here, Rachel Allen looks at a systematic review that set out to address that question.

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The antidepressant effects of ketamine are confirmed by a new systematic review and meta-analysis

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Helge Hasselmann summarises a new systematic review and meta-analysis, which confirms the antidepressant effects of ketamine.

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Exercise may help reduce falls in older people with dementia, but does the burden outweigh the benefit?

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Rosalyn Nelson writes her debut blog on a recent systematic review, which looks at the effectiveness of exercise programs to reduce falls in older people with dementia living in the community.

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Musculoskeletal physiotherapists' views and use of psychological interventions

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In her first guest blog, Larissa Kempenar, lecturer in physiotherapy at Glasgow Caledonian University, discusses a systematic review of musculoskeletal physiotherapists’ perceptions and use of psychological interventions. The review also examined how skilled physiotherapists felt to use these interventions within their practice.

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