Antidepressants: benefits and harms in children and adults

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Samei Huda discusses the findings of a recent review into suicidality and aggression during antidepressant treatment. The systematic review and meta-analyses were based on clinical study reports and included some important adverse effects of antidepressants in children and young people.

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Aripiprazole for treatment-resistant depression in older adults

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Sarsha Wilson publishes her debut blog about a recent RCT on the efficacy, safety and tolerability of augmentation pharmacotherapy with aripiprazole for treatment-resistant depression in later life.

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Are Internet interventions cost-effective for mental health?

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Chris Sampson looks at a systematic review of the economics of Internet interventions for common mental health problems such as depression and anxiety.

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Psychotic-like experiences associated with self-harm, according to new systematic review, but further research is needed

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Katrina Witt critiques a recent systematic review of psychotic-like experiences and the risk of self-harm and suicide in the general population.

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Psychosocial suicide prevention in youth: is the evidence strong enough?

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Rachel Upthegrove appraises a recent systematic review of psychosocial suicide prevention for youth, which leaves her calling for better evidence to support investment in universal school-based interventions.

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Suicide risk assessment and intervention: need for a new approach?

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Olivia Kirtley and Alys Cole-King consider the implications of a new BMJ review on suicide risk assessment and intervention in people with mental illness.

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Varenicline and the risk of neuropsychiatric adverse events and death

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Natasha Clarke publishes her debut Mental Elf blog about a new systematic review and meta-analysis investigating the risk of neuropsychiatric adverse events associated with the smoking cessation drug varenicline.

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Improving mental health literacy in the classroom: new HeadStrong RCT

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Lisa Burscheidt reports on an RCT of the Headspace mental health literacy intervention and the impact it has on the mental health literacy, stigma, help-seeking and mental health of a group of young people in Australia.

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Interpersonal therapy and imipramine may be effective at reducing suicidal ideation in depression, but more research needed

Susie Johnson considers how effective conventional depression treatments are at reducing suicidal ideation in depression. The new study she summarises concludes that interpersonal therapy and antidepressants can also reduce suicidal ideation.

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Bullying and cyberbullying increase the risk of suicidal ideation and suicide attempts in adolescents

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Bullying is just not good for you.  Here on Mental Elf, we’ve already picked some great examples of studies demonstrating this.  André blogged about how bullied children are more likely to develop psychosis, and how bullies are at higher risk for teen pregnancy, and not so long ago, I told you how Wolke et al demonstrated that [read the full story…]