In her debut blog (and the Mental Elf’s first body-focused repetitive behaviours blog), Mallory Moore summarises a systematic review investigating whether internalised stigma can predict depression.
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Kirsten Lawson and Douglas Badenoch review the new randomised controlled trial by Cleare et al, published today in The Lancet Psychiatry, directly comparing the clinical and cost effectiveness of lithium and quetiapine as augmentation treatments for patients with ‘treatment resistant depression’.
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Dr Rachel Reid-McCann discusses the latest research on dosage of levonorgestrel-releasing intrauterine system (LNG-IUS) and the risk of depression. A well conducted study from Denmark “provides evidence of a dose-dependent association between LNG exposure and risk of subsequent depression across three dosages”.
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Ella Tuominen looks at a study of childhood adversity and ‘treatment resistant depression’ and asks: Can long-term psychoanalytic therapy provide deeper healing for chronic depression than CBT?
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Julian Mutz discusses the results of a new 10-week RCT assessing home-based brain stimulation for depression, which suggests that tDCS may be a safe, acceptable and efficacious treatment for moderate depression.
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Clare Gerada and Ruby Wiltshire summarise a new scoping review of UK-based research on the treatment of harmful gambling, which finds a complete lack of high quality intervention studies to support decision making.
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Tim van der Es discusses a recent paper that investigates whether ADHD causally increases the risk of subsequent major depression diagnoses. The study findings underscore the need for effective treatment and assessment of ADHD and a requirement for a deeper understanding of the potential causal mechanisms linking ADHD and depression.
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Ruby Tsang summarises a recent longitudinal study of trajectories of inflammation in youth and risk of mental and cardiometabolic disorders in adulthood, which finds that high levels of inflammation in childhood may be linked to an increased risk of psychosis, depression and insulin resistance in early adulthood.
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Amanda Sabo and Louise La Sala summarise a recent review investigating the impact of social media use on internalising symptoms in adolescents from clinical and community samples.
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Shuichi Suetani blogs a new study published today in The Lancet Psychiatry, which suggests that those patients who might benefit most from evidence-based guidance are the least represented in clinical trials about ADHD medication. Is it time to reconsider the value we place on RCTs when they do not include the vast majority of people who need help?
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