Meenakshi Shukla summarises a systematic review exploring the trajectory of blood pressure, body mass index, cholesterol and incident dementia.
[read the full story...]Are changes in blood pressure and weight linked to later dementia?
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For: systematic review
Composite resin or amalgam fillings for permanent posterior teeth
This updated Cochrane review of the efficacy and safety of direct composite fillings versus amalgam fillings included 8 RCTs. Low‐certainty evidence suggests that composite resin restorations may have almost double the failure rate of amalgam restorations.
[read the full story...]How risky for developing psychosis are ‘At Risk Mental States’ in youths?
In their debut blog, Martin Rimvall and Pia Jeppesen summarise a recent systematic review and meta-analysis exploring psychosis risk in children and adolescents with an ‘At Risk Mental State’.
[read the full story...]Topical anaesthesia: Does it reduce pain perception of local anaesthetic injections?
This review of the effectiveness of topical anaesthesia in in reducing pain during local anaesthetic injections for dental procedures included 22 RCTs. Statistically significant differences were seen during needle puncture with topical anaesthetic use in the maxilla and palate but not the mandible.
[read the full story...]Intraoral stents to reduce oral toxicity of radiotherapy
This review assessing the effectiveness of intraoral stents in reducing toxicities in oral cavity induced by radiotherapy in head and neck region included 7 small studies. While the analysis suggests a beneficial effect from the use of intraoral stents the included studies only provide verylow certainty evidence so further high-quality RCTs are needed.
[read the full story...]Opioid Agonist Treatment associated with 50% lower risk of mortality, but political epiphany still needed to reduce drug-related deaths
Ian Hamilton appraises a systematic review and meta-analysis on the association of opioid agonist treatment with all-cause mortality and specific causes of death among people with opioid dependence.
[read the full story...]Denture stomatitis: Are natural products effective?
This review comparing topical natural substances with conventional antifungals in the treatment of denture stomatitis included 17 studies 14 of which were RCTs. A wider range of natural products were tested and showed similar efficacy to antifungals however, almost all the studies were at high risk of bias so the certainty of the evidence is very low.
[read the full story...]Should clinicians be developing a suicide safety plan with their patients?
Felicity Pearce, Bani Kahai and Derek Tracy summarise a recent meta-analysis examining safety planning-type interventions for suicide prevention.
[read the full story...]Fibre or metal posts for restoring endodontically treated teeth?
This review evaluating the difference between fibre and metal posts for endodontically treated teeth included 10 studies 6 of which were RCTs. The findings suggest no differences in outcomes between the two main types of post assessed. However, the evidence is of low certainty.
[read the full story...]New review suggests that PTSD may be a modifiable risk factor for dementia
Anjuli Kaul blogs about a new systematic review and meta-analysis of longitudinal cohort studies, which explores the relationship between PTSD and all-cause dementia.
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