This review of the efficacy of topical sialogogue spray containing malic acid 1% for treating xerostomia included 5 RCTs involving 244 patients. While the findings suggested a benefit the available studies are small, of short duration and none are at low risk of bias.
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This review of the most effective method of anaesthesia for mandibular posterior teeth with symptomatic irreversible pulpitis included 22 RCTs. The findings suggest that buccal infiltraion and inferior alveolar nerve block ,Vazirani-Akinosi nerve block and introsseus injections performed better but the evidence was only of low to very low certainty.
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Shubhangi Karmakar summarises a systematic review on the effects and feasibility of psychological interventions to reduce inattention symptoms in adults with ADHD, which highlights significant uncertainty in the field.
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This Cochrane review update of interceptive procedures included 4 RCTs to promote the eruption of palatally displaced permanent canines (PDCs) involving a total of 199 patients. The findings indicate that extraction of the primary canine man increase the the proportion of erupted PDCs but the evidence is very uncertain.
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In their debut blog, Zill-e-Huma & colleagues explore a systematic review finding family interventions beneficial for child anxiety and depression in low and middle income countries.
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This Cochrane review update of the effects of different orthodontic treatments for posterior crossbites included 31 RCTS eight of whihc were at low risk of bias. They found that for children iaged 7 to 11 years old), quad-helix and expansion plates were more beneficial than no treatment for correcting posterior crossbites.
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This Cochrane review of the effects of orthodontic interventions for preventing or correcting crowded teeth in children included 24 RCTs. A wide range of interventions were assessed typically is small single studies so the available evidence is of very low certainty.
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Michael Ostacher critically appraises and summarises a recent Cochrane systematic review, which presents the latest best evidence on the efficacy of lamotrigine in the maintenance treatment of bipolar disorder.
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This review of whether chemotherapy, in addition to radiotherapy and/or surgery for oral cavity and oropharyngeal cancer, results in improved overall survival included 100 studies. the findings indicated some benefit only when used in a few specific circumstances.
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This Cochrane review update of the diagnostic test accuracy of conventional oral examination, vital rinsing, light-based detection, mouth self-examination, remote screening, and biomarkers, used singly or in combination, for the early detection of OPMD or OSCC in apparently healthy adults included 18 studies.
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