Choi in a trial in 2009 found that an intravenous bolus administration of tranexamic acid at 20 mg/kg reduces blood loss compared with placebo during bimaxillary osteotomy. The aim of this trial was to test whether the use of tranexamic acid in an irrigant fluid would decrease blood loss during orthognathic surgery Forty patients undergoing [read the full story…]
The use of illicit drugs or alcohol(substance using) is a most common precipitator of facial injuries among socioeconomically disadvantaged populations. Reducing these risky behaviours could improve outcomes and reduce potential for reinjury. The aim of this study was to assess whether a culturally competent, personalized motivational intervention incorporated into surgical care could significantly reduce existing [read the full story…]
The mental health charity Mind have published the findings of a three year study which explores whether regular proactive reviews delivered by nurses in GP practices results in better mental health and social outcomes for people living with depression. The study was a randomised controlled trial carried out by a research team at University College London. [read the full story…]
Articaine is a common local anaesthetic agent that shows greater lipid solubility than lidocaine, allowing enhanced diffusion through nerve sheaths. It also has an increased potency compared with lidocaine. The aim of this study was to compare the anaesthetic efficacy of 4% articaine with epinephrine (1:100,000) and without epinephrine in inferior alveolar nerve block anaesthesia [read the full story…]
The aim of this single-blind cross-over study was to compare the performance of three different toothbrush models in the control of dental biofilm and maintaining a healthy gingival condition. The sample was randomly divided into three groups (A, B and C), each of which used one of the three toothbrushes tested. The brushes had bristles [read the full story…]
It has been widely reported that antipsychotics have been frequently used to treat the behavioural and psychological symptoms that affect people with dementia and that this course of action has resulted in an estimated 1,800 excess strokes and 1,600 excess deaths in the UK alone. This double-blind, parallel-group, placebo-controlled randomised trial looks at one of the [read the full story…]
The aim of this trial was to assess the efficacy of a topical gel with triester glycerol oxide for treating ulcerations related to new complete dentures was studied and compared with a placebo gel. Fifty edentulous patients who received new maxillary and mandibular complete dentures were enrolled in this double-blind clinical study. Twenty-five patients received [read the full story…]
The aim of this trial was to compare the short- and long-term effectiveness of a prefabricated occlusal appliance with that of a stabilization appliance when treating headache in patients with myofascial pain. A group of 66 patients attending two centres for Stomatognathic Physiology in Sweden and Finland 94% of whom suffered concomitantly from headache were [read the full story…]
The PEARLS Program is a team-based approach, involving counsellors, psychiatrists and medical providers, designed to reduce depressive symptoms and improve quality of life in adults with epilepsy. It was developed by a team at the University of Washington and has been studied through two randomised controlled trials, the second of which measures the long-term benefits of [read the full story…]
We know very little about how to increase the safety and wellbeing of mothers who experience intimate partner violence. A good deal of the research in this field focuses on treatments delivered by health professionals, but this cluster randomised trial from Melbourne Australia looked at the impact that non-professional mentor support can have in reducing [read the full story…]
