This review of the effectiveness of locally delivered adjunctive antibiotic treatment during periodontal surgery on clinical outcomes included 9 RCTs. While the findings suggested that adjunctive locally delivered antibiotics could improve some clinical sutcomes they evidence was limited and of very low certainty.
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This review of the osteoradionecrosis rate in patients with head and neck cancer having toothth extraction performed before radiotherapy included 8 mainly retrospective studies. The pooled incidence rate was estimated at 2.2% (95% CI: 0.6% to 3.9%) although none of the studies controlled for other risk factors.
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This review of the effectiveness of leukocyte-and platelet-rich fibrin (L-PRF) and advanced-platelet-rich fibrin (A-PRF) in mandibular third molar extraction included 10 RCTs. While the findings suggest some benefits the studies are small and limited in number so the findings should be interpreted cautiously.
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This review comparing compare the success rate of five tooth-coloured materials for class II restorations in primary molars included 10 RCTs. No differences in failure rates were seen for composite resin,resin-modified glass ionomer cement or compomers although all included studies were at high risk of bias.
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Jessica Scaife reviews a individual patient data meta-analysis exploring the continuation of antidepressants versus sequential psychological interventions to prevent relapse in depression.
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This review aimed to evaluate the association of preoperative factors or intraoperative factors with treatment outcomes of vital pulp therapy. 14 RCTs were included with the findings indicating a 93.2% (95%CI; 91-6% to 94.9%) success rate using contemporary bioceramic material based on low certainty evidence.
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This review of the effectiveness of locally administered antibiotics in the treatment of peri-implantitis included 12 small studies 7 of which were RCTs. While the findings suggest a small additional benefit with antibiotic use however the clinical importance of this is debatable.
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Manas Dave takes a look at this review aiming to identify the potential risk factors associated with the development of oral mucositis in paediatric patients. While a range of risk factos are higlighted it is worth noting that 80-100% of all children having chemotherapy experience some degree of mucositis.
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This review of the effectiveness of warm saltwater mouthwashes in preventing incidence of dry socket following tooth extraction included 8 RCTs. Only one of the included studies was considered to be at low risk of bias with the findings indicting that saltwater was more effective than no moutwash but less effective than chlorhexidine.
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This review of malocclusion and the severity of dental caries among children and adolescents in the permanent dentition included 5 cross-sectional studies suggesting an association. However the quality of the evidence is limited so should be interpreted cautiously.
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