Results: 1413

For: meta-analysis

Structured exercise reduces depression in older people, according to new systematic review

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Regular readers of the Mental Elf will recall the blogs (Here is the evidence for exercising if you are depressed and New Cochrane review shows that exercise helps with depression) I wrote back in June and July about the evidence for exercising if you have depression. A new systematic review was published in the British [read the full story…]

More research is needed for cognitive behavioural therapy to help men who commit domestic violence

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Men who physically abuse their partners are often treated with cognitive behavioural therapy (CBT). Men sometimes sign up to these treatment programmes voluntarily, but are also sometimes obliged to participate by a court order. CBT can help change behaviour and also break established thinking patterns and beliefs, but is there any reliable evidence that this [read the full story…]

How should we personalise treatment for adults with depression?

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One of the criticisms that health professionals sometimes make of evidence-based research is that individual studies or reviews do not apply to the specific patient they are caring for. Of course, each patient is unique with their own values and preferences, as well as their own particular clinical characteristics, genetic make-up, biological markers and sociodemographic [read the full story…]

More research needed before polyunsaturated fatty acids can be recommended for ADHD in children and adolescents

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Drug treatments are commonly used to treat children and young people with attention deficit hyperactivity disorder (ADHD). Methylphenidate and amphetamine are two of the most popular, but these are not effective for all patients and sometimes cause problematic side effects. Children and adolescents with ADHD have been shown to have significantly lower plasma and blood [read the full story…]

Losing weight on antipsychotics. New systematic review looks at diet and exercise

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Weight gain is one of the side effects that people who take antipsychotic drugs complain of the most. Obesity is common in this population and this can often lead to cardiovascular problems and a far shorter life expectancy than the rest of the population. As a result, there is a great deal of interest in [read the full story…]

Haloperidol reduces mania a little faster than second-generation antipsychotics, according to systematic review

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There are a range of treatment options for people with bipolar disorder who are experiencing a manic episode. An important part of this treatment is to reduce the symptoms of mania and provide the individual with some level of normality. I blogged this time last year about a meta-analysis in the Lancet that showed that [read the full story…]

The dose-response association between psychological distress and mortality, new BMJ meta-analysis shows the link

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There is an increasing body of evidence showing that depression and anxiety are linked with other health conditions like cancer and cardiovascular disease. I’ve blogged about the link between depression and stroke, and there are a number of other studies that show an association between psychological distress (the symptoms of depression and anxiety) and mortality, [read the full story…]

Treating depression and anxiety with the benzodiazepine alprazolam: new Cochrane review recommends caution

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Antidepressants and psychotherapies are the mainstay for treating depression, but another option is the benzodiazepine drug alprazolam, which is recommended for treating depression when anxiety is also involved. Some doctors prescribe a short course of benzodiazepines to help depressed and anxious patients, but this is not supported by NICE guidance. High-potency tranquillisers like alprazolam are [read the full story…]

Review finds insufficient evidence base for the view that violence, sexual, or criminal risk can be predicted

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Normally, we at the Learning Disabilities Elf like to look at learning disability specific research, but we thought this review of the utility of risk assessment tools was interesting and relevant to people with learning disabilities who come into contact with psychiatric and criminal justice services. Risk assessment research stresses the dynamic nature of predictors [read the full story…]

Risk assessment tools do not accurately predict the risk of repeat offending, according to new systematic review

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Risk assessment tools are widely used in psychiatric hospitals and criminal justice systems to help predict violent behaviour and inform sentencing and release decisions. Yet their predictive accuracy remains uncertain and expert opinion is divided, according to a new systematic review published in the BMJ. An international team of researchers led by Seena Fazel from [read the full story…]