In his first blog for the Dental Elf Rajpal Tattar take a look at a review of the diagnostic accuracy of salivary biomarkers for the detection of oral squamous cell carcinoma (OSCC). The review considers two biomarkers, cytokeratin 19 fragment (CYFRA 21-1) and for matrix metalloproteinase-9 (MMP-9) but there is no conclusive evidence for either at present.
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11 RCTs were included in this Cochrane review which looked at the relative effectiveness of fissure sealants compared with fluoride varnishes for the prevention of caries in the occlusal surfaces of permanent teeth.
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This review of metastasis to the oral and maxillofacial region included 217 studies (190 case reports,24 case series ). Metastasis were uncommon, but identified from 29 primary sites, the most common sites being lung the lungs (20.97%), breast (12.06%) and kidney (11.78%).
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This review of the effect of powered and manual toothbrushes on oral health during fixed applinace orthodontic treatment included 7 RCTs. The findings suggest no diference between the toothbrush types. However the quality of the evidence is low and the studies are of short duration.
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This review of sub-gingival chlorhexidine chips as an adjunct to scaling and root planing in patients with chronic periodontitis included 15 RCTs involving 620 patients in total. Findings suggest an additional improvement with adjunctive use of chlorhexidine chips.
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The review of the use of botulinum toxin type A injections in the management of primary bruxism in adults included 10 studies. Only 6 of the included studies were RCTs and the studies were generally small are very hetrogeneous so additional well designed and conducted RCTs are needed.
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This review of the use of botulinum toxin (BONT-A) for pain-relief in patients with persistent idiopathic dentoalveolar pain included just 3 small uncontrolled studies providing a very limited amounh of very low quality evidence.
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This review comparing the duration of fixed orthodontic treatment between adults and adolescents included 11 studies the majority of which were retrospective. Meta-analyses indicated no statisticall or clinical differences in duration although the quality of the available evidence was low to very low.
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13 studies involving a total of 3885 patients were included in this review of the prevalence of hyposalivation in individuals aged ≥ 60 years. The findings suggest an overall prevalence of 33.4% (95%CI; 23.9- 43.6%).
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This Cochrane review update of the optimal recall interval of dental check-up for oral health in a primary care setting included 2 RCTs. The findings show little to no difference between six‐monthly and risk‐based check‐ups in tooth decay, gum disease and quality of life after four years.
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