Burning mouth syndrome treatments – network meta-analysis

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This review of all treatments for the relief of pain associated with burning mouth syndrome (BMS) as compared with no intervention or placebo included 44 RCTs. There was moderate certainty evidence that clonazepam is likely to reduce the pain of BMS compared with placebo.

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Peri-implantitis – Surgical treatment with or without adjunctive graft material

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This review of the surgical treatment of peri-implantitis alone or in combination with adjunctive graft material included 5 small RCTs. The findings suggest improvements in marginal bone level (MBL) with graft material but the findings should be interpreted very cautiously because of the limited amount and quality of the evidence.

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Adjunctive therapies during supportive periodontal care

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This review of adjunctive therapies during supportive periodontal care (SPC) in patients with residual/relapsing pockets included 12 studies that currently provide insufficient/poor evidence to determine the efficacy of adjunctive strategies to improve SPC.

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Antibiotics for dental infections – Short or long duration courses?

Many drugs are licensed for use in Generalised Anxiety Disorder (GAD), but it is unclear what works best.

This review comparing short (3–5 days) or longer courses (≥7 days) of antibiotics for the treatment of dental infections in general practice only included one small RCTs. No differences were seen between short an dlong courses but the findings should be interpreted cautiously becaise of the limited data available.

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Metronidazole for treatment of non-periodontal dental infections

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This review of whether metronidazole used as monotherapy or in addition to a β-lactam antibiotic offers any additional benefit over β-lactam monotherapy in non- periodontal dental infections includes 3 RCTs. The findings suggest that metronidazole does not provide superior clinical results compared to β-lactam antibiotics for the treatment of non-periodontal dental infections. However the evidence is limited and of low quality.

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Dental erosion in children and gastro-oesophageal reflux disease

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This review of the association between gastro-oesophageal reflux disease (GERD) and dental erosion in children included 13 observational studies. The findings suggest positive association association between GERD and dental erosion in children however this should be interpreted cautiously because of the wide variety of diagnostic methods used in the included studies.

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Periodontal treatment for preventing cardiovascular disease in people with periodontitis

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This Cochrane review update on the effects of periodontal therapy for primary or secondary prevention of CVD in people with chronic periodontitis includes 2 studies which provide very low certainty evidence. No additional studies have been included since the last update in 2019.

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Oral erythroplakia: malignant transformation rate

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This review of the malignant development rate of oral erythroplakia and associated risk factors included 10 studies involving a total of 441 patients. Meta-analysis of 3 studies suggest a malignant development rate = 19.9% (95%CI; -1.6% to 41.4%).

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Burning mouth syndrome – topical interventions

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This review assessing the effectiveness of topical interventions in the management of burning mouth syndrome (BMS), based on the core outcome domains recommended by the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT) includes 8 RCTs and higlights the need to apply standardised outcome measures in future studies.

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Mastication and chronic disease in older adults

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In this blog Carly Ross assess a review of the associations between objectively assessed masticatory performance, chronic systemic diseases and physical function in older adults.

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