123 RCTs were included in this Cochrane review of local anaesthetic agents for preventing pain during dental treatment. 14 types of local anaesthetic were included evidence to support the use of one over another was limited so further research is needed to clarify the effectiveness and safety of one local anaesthetic over another.
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This large multicentre, cluster randomised controlled compared the clinical effectiveness and cost-effectiveness of theory-based, personalised oral hygiene advice or scale and polish’ with routine care in improving periodontal health in dentate adults attending general dental practice.
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This review of perioperative systemic corticosteroids on clinically important outcomes in patients undergoing orthognathic surgery identified 8 small RCTs. A reduction in facial oedema was seen in those receiving systemic corticosteroids. However the quality of the studies is limited and there is lack of evidence on other outcomes or adverse effects.
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This review of regenerative endodontic treatment included 14 small observational studies of limited quality suggesting a possible influence of apical diameter on clinical outcomes.
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This review of glutaraldehyde or fluoride varnish for dentine hypersensitivity included just 4 small RCTs . The findings suggest a benefit in favour of glutaraldehyde at 7 days but the short-term nature of the studies and their limited quality means these findings should be interpreted cautiously.
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This review of the adjunctive effect of statins on mechanical periodontal therapy included 15 studies 12 of which were RCTs. The findings suggest a positive effect on probing pocket depth, clinical attachment level, and intrabony defects but the overall quality of evidence is considered to be low.
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27 studies were included in this review of the failure rates of palatal implants & mini-screws for supplementing anchorage during orthodontic treatment. Failure rates were low and similar for both implants & mini-screws.
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17 studies, none of which were at low risk of bias, were included in this review of the effect of type of instrumentation on post endodontic pain. The findings suggest lower incidence and intensity of postoperative pain with rotary instruments compared to hand files.
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22 RCTs were included in this review of the influence of the monomer HEMA in the formulation of dental adhesive systems suggests that HEMA-free adhesive systems do not have better clinical performance of the non-carious cervical lesion restorations than HEMA-containing systems.
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Opportunity to participate in an eDelphi survey to identify core outcomes when assessing the effects of treatment interventions for managing carious lesions.
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