Why do people who were maltreated as children face higher risks of both mental and physical illness? A new Mendelian randomisation study suggests that metabolic markers — like triglycerides and blood sugar — may be part of the chain connecting adversity to later multimorbidity.
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Negative core beliefs like “I’m worthless” or “people can’t be trusted” are linked to hallucinations, paranoia, and suicidality. This new systematic review shows how deep-rooted schemas shape psychosis, and what this means for psychological therapies.
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Fragmented systems leave many homeless women with severe mental illness excluded from care, re-traumatised, and at risk. This study developed a gender-sensitive housing model that integrates tertiary care, transitional homes, and community reintegration; centring dignity, safety, and recovery.
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Beta-blockers like propranolol are being prescribed more often for anxiety in UK primary care, even though they don’t appear in national guidelines. This new qualitative study explores why GPs turn to them, and what that says about evidence, safety, and patient choice.
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Many displaced people reach safety only to find new challenges waiting. This new qualitative systematic review synthesises the experiences of 490 refugees, revealing the mental, social, and structural barriers they face in trying to integrate.
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This brand new Lancet Psychiatry paper looks across 38 longitudinal cohort studies to uncover how parenting and family dysfunction predict later self-harm or suicidality. The findings may surprise you.
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Dona Mathews highlights a new study showing a doubled risk of depression after a medical diagnosis – especially in the first month post-diagnosis, for those who are hospitalised for their medical condition, those with multiple medical conditions, those over 60, and for women.
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Inflammation is a key factor in depression for many people. This new RCT used an experimental immune challenge to explore how individuals with high inflammation respond differently—shedding light on a distinct biological subtype of depression.
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Despite strong evidence, collaborative care remains underused in the NHS. This blog explores new findings that highlight which components of the model are most effective in reducing depression symptoms.
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The Education for Wellbeing programme, funded by the Department for Education, was one of England’s largest school-based mental health research initiatives. It included two major trials (AWARE and INSPIRE) testing universal mental health approaches in schools between 2018 and 2024. What did these big studies really find?
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