John Baker reviews a recent participant-level meta-analysis of six placebo-controlled studies, which looks at the initial severity of schizophrenia and the efficacy of antipsychotics including Olanzapine, Risperidone and Amisulpride.
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Ioana Cristea reviews a recent RCT that found no effects of positive imagery-based cognitive bias modification, delivered as a web-based treatment for people with depression.
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Do you know that over 1 million hip replacements are carried out each year? The majority of Total Hip Replacements are for people with severe arthritis of the hip that causes pain and reduction in function. We elves wanted to know for someone with osteoarthritis of the hip what are the medium term health related [read the full story…]
André Tomlin presents the results of the PREVENT RCT published today in The Lancet, which investigates the effectiveness and cost-effectiveness of mindfulness-based cognitive therapy compared with maintenance antidepressant treatment in the prevention of depressive relapse or recurrence.
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In her debut blog, Nicky Butler considers a systematic review, which explores whether rehabilitation following lumbar spinal decompression surgery is effective.
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We learnt in an earlier post about the burden of musculoskeletal conditions that osteoarthritis (OA) develops around the age of 50. Blimey some of our elves are approaching that age. What can we do to help any symptoms that start to develop? We eleves are always looking to stay fit and thought that exercise might help. But [read the full story…]
In this blog, Lesley Dawson considers a systematic review examining musculoskeletal Intermediate Care pathways to evaluate their effectiveness, outcomes and identify gaps in evidence.
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Self injurious behaviour in people with learning disabilities, as well as causing physical harm, can have a major impact on quality of life. It is not entirely clear why people engage in self injurious behaviours, but one theory suggests that it may be connected with an opiate euphoria. If this is so, it might be that medications that blocked these opiates might impact on levels of SIB.
Here, Rachel Allen looks at a systematic review that set out to address that question.
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Helge Hasselmann summarises a new systematic review and meta-analysis, which confirms the antidepressant effects of ketamine.
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Caroline Struthers critically appraises a recent RCT of diet, exercise, cognitive training and vascular risk monitoring to prevent cognitive decline and dementia in at-risk Finnish women.
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