This ADA-EBD critical summary looks at systematic review by Sgolastra et al from 2012 that addressed the question of whether the use of amoxicillin/metronidazole (AMX/MET) as an adjunct to scaling and root planning (SRP) was more effective than SRP alone in the treatment of chronic periodontitis. The appraisers considered that searching an analysis of the [read the full story…]
The risks of congenital malformations and impact of cognitive development after foetal exposure to anti-epileptic drugs has been known for some time. Sodium valproate is a frequently used drug for epilepsy and other disorders (including bipolar disorder and migraine). The researchers aimed to examine the link between foetal exposure and subsequent development of autism. Methods [read the full story…]
Bipolar disorder features as one of the top ten disabling disorders for working age adults. There are numerous risks including suicide, increased mortality and reduced social functioning associated with the disorder. Key to enabling recovery is preventing acute episodes from occurring, with each episode increasing the risk of future ones. Therefore ensuring long-term maintenance treatment [read the full story…]
There is a limited amount of good quality research being published about bipolar disorder, particularly investigating the early stages. Bipolar is associated with a high risk of relapse and this risk of relapse increases with the number of previous episodes. Observational studies suggest that early intervention may improve both course and outcome, but currently progression [read the full story…]
Making the decision to consent to medical treatment requires access to information, presented in clear and understandable ways. There is evidence that that people with learning disabilities do not always understand information about medications they are prescribed, for example from the medication matters project carried out at the Norah Fry centre which produced a series of [read the full story…]
Earlier this month (Dental Elf 13th Feb 2013) we reported on a study looking at whether systemic antibiotics were necessary for the placement of dental implants. That study suggested that antibiotics were not necessary for the placement of single implants. Today we look at another study that looked at the influence of pre-operative antibiotics on [read the full story…]
The use of systemic antibiotics during dental implant placement has been controversial, with some authors claiming higher survival rates with peri-operative antibiotic use. The aim of this multi-centre trial was to assess the effect of various systemic antibiotic prophylaxis regimes on patient- reported outcomes and postsurgical complications in patients undergoing conventional implant placement. Following establishment [read the full story…]
Williams syndrome is a neuro-developmental genetic disorder caused by gene deletion estimated to have a prevalence of 1 in 7,500 to 1 in 20,000 live births. Previous studies have identified anxiety as part of the behavioural phenotype of the syndrome The authors of this US study set out to look at the effectiveness and adverse [read the full story…]
In March 2008 the National Institute for Health and Clinical Excellence (NICE) produced new guidance recommending the cessation of antibiotic prophylaxis for all patients at risk of infective endocarditis undergoing dental and a wide range of other invasive procedures. At the time this was controversial and although there were similar changes to recommendations in American [read the full story…]
Tooth extraction is probably the most commonly conducted surgical procedure. Teeth are normally extracted because of severe dental caries or periodontal (gum) infection, although they are also removed because they are poorly aligned or developed. To aim of this Cochrane review was to determine the effect of antibiotic prophylaxis on the development of infectious complications [read the full story…]
