Results: 119

For: medicines

Ketamine and suicidal ideation: French trial finds modest short-term effects

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Anya Borissova reviews a French trial that claims to be evidence that “ketamine is rapid, safe in the short term, and has persistent benefits for acute care in suicidal patients”.

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Ketamine “shows promise” as an anti-suicidal ideation agent, but will this promise ever be realised?

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Rosalind McAlpine and Karel Kieslich summarise a recent systematic review which focuses on the rapid anti-suicidal ideation effect of ketamine.

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Lamotrigine in the maintenance treatment of bipolar disorder

Lamotrigine, an anticonvulsant drug, is licensed in the United States for the maintenance treatment of bipolar I disorder and in the UK to prevent depressive episodes in bipolar disorder. Hashimoto and colleagues (2021) performed a Cochrane Intervention Review to explore whether lamotrigine is effective and safe compared to the most established maintenance treatment, lithium, and placebo.

Michael Ostacher critically appraises and summarises a recent Cochrane systematic review, which presents the latest best evidence on the efficacy of lamotrigine in the maintenance treatment of bipolar disorder.

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Peri-implantitis: Are locally administered antibiotics effective?

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This review of the effectiveness of locally administered antibiotics in the treatment of peri-implantitis included 12 small studies 7 of which were RCTs. While the findings suggest a small additional benefit with antibiotic use however the clinical importance of this is debatable.

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ADHD: which medications are most effective and safe?

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In his debut blog, Franco De Crescenzo summarises a narrative review that finds good evidence for the short-term pharmacological treatment of ADHD.

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Can ketamine metabolites and gamma power help predict clinical response for ‘treatment resistant depression’?

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Anya Borissova summarises a recent randomised placebo-controlled trial that evaluated ketamine metabolites, clinical response, and gamma power for major depression.

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Patients’ experience of ketamine treatment for depression: the ‘Ketamine and me’ project

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In her debut blog, Harmony Jiang reviews a recent qualitative study exploring patients’ experience and response to ketamine treatment for depression.

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Drug treatment of ADHD in children and young people with ASD #CAMHScampfire

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Douglas Badenoch appraises an up-to-date systematic review and decision pathway for the drug treatment of ADHD symptoms in young people with autism spectrum disorder.

Follow #CAMHScampfire on Twitter at 5pm BST on Tuesday 25th May for an online journal club discussing this paper. Or sign up now to join the free webinar hosted by ACAMH.

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Living in anxious times? The rise of anxiety disorders in the UK

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Alice Grishkov and Derek Tracy explore a recent paper, which finds that generalised anxiety disorder is on the rise in the UK, especially in young women.

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Cost-effective strategies for mental health workplace intervention

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Chris Sampson summarises a review on the cost-effectiveness of mental health workplace interventions, which presents up-to-date evidence on the different things that employers can do to help those in their workforce affected by mental health problems or substance misuse.

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