Results: 106

For: medicines

Lithium for bipolar disorder: the best maintenance mood stabiliser protection against self-harm and suicide?

3779655817_65e65a76a4_o

Michael Ostacher provides a robust appraisal of a recent UK cohort study that suggests bipolar disorder patients taking lithium had reduced self-harm and unintentional injury rates, when compared with patients taking valproate, olanzapine or quetiapine.

[read the full story...]

Third molar removal: antibiotics reduced risk of dry socket

shutterstock_133048361

This review of antibiotic prophylaxis for the removal of third molars included 22 RCTs and suggest that antibiotic use lowered the infection risk by 60%. The number pf patients needed to treat to prevent one infection was 14 (95%CI;11-19).

[read the full story...]

Evidence-based guidelines for treating bipolar disorder

2704560472_63b23c8c4e_b

Joseph Hayes summarises the recent British Association for Psychopharmacology guidelines for the treatment of bipolar disorder, and compares their recommendations with those found in the NICE bipolar disorder guidance from 2014.

[read the full story...]

Cardiovascular safety of methylphenidate

6856794287_cbb9e26110_b

Samuele Cortese considers the findings of a recent nationwide self controlled case series study of the cardiovascular safety of methylphenidate use in children and young people with ADHD.

[read the full story...]

Cochrane find no evidence for as required PRN medication for mental health inpatients

4711660113_49676b8c32_b

John Baker summarises an updated Cochrane review on ‘as required’ PRN medication regimens for seriously mentally ill people in hospital, which finds no randomised controlled trials that support this widely used intervention.

[read the full story...]

Nalmefene for alcohol dependence: new evidence casts doubt over NICE recommendations

5006945413_c9e97ac841_b

Matt Field presents new evidence on the risks and benefits of nalmefene in the treatment of adult alcohol dependence, which casts further doubt over the controversial recommendations made by NICE and the European Medicines Agency.

[read the full story...]

Amphetamines and methylphenidate for paediatric ADHD: meta-analysis of n-of-1 trials

1850210315_a332da28ea_b

Samuele Cortese publishes his debut Mental Elf blog on a meta-analysis of n-of-1 trials, which shows that amphetamine derivatives and methylphenidate are superior to placebo, in the short term, for paediatric ADHD.

[read the full story...]

Psychotropic medication in pregnancy: new evidence may help achieve a safe balance

pregnant with ipad

Joanne Wallace considers a recent health technology assessment on the risks and benefits of psychotropic medication in pregnancy, which supports previous associations between valproate and adverse child outcomes.

[read the full story...]

Mental illness, challenging behaviour and psychotropic drugs #UCLJournalClub

1280px--The_Conversation-,_1963_-_NARA_-_558908

Join us at 2-3pm on Wednesday 18th May for the #UCLJournalClub, which will be live broadcasted on YouTube and live tweeted by the @LearningDisElf

[read the full story...]

What do you want from your psychiatric medication?

4741451457_6344b99835_b

John Baker presents a systematic review of preferences for medication-associated outcomes in mental disorders, which concludes that we just don’t know what value mental health service users place on the different outcomes that come from taking psychiatric medication.

[read the full story...]