Alice Grishkov and Derek Tracy explore a recent paper, which finds that generalised anxiety disorder is on the rise in the UK, especially in young women.
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Chris Sampson summarises a review on the cost-effectiveness of mental health workplace interventions, which presents up-to-date evidence on the different things that employers can do to help those in their workforce affected by mental health problems or substance misuse.
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This review of the efficacy of prophylactic oral antibiotics in the management of post-operative endodontic symptoms included 10 RCTs. The findings and show that there is no superiority in using adjunctive antibiotics for the prevention of post-operative endodontic symptoms.
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This Cochrane review of the effects of systemic antimicrobials as an adjunct to scaling and root planing (SRP) for the non-surgical treatment of patients with periodontitis identified 45 RCTs. However the evidence is of very low certainty to inform tclinicians and patients if adjunctive antibiotics are beneficial.
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Jodi Rintelman writes her debut elf blog on the first randomised controlled trial on the efficacy and safety of intranasal esketamine as an adjunctive treatment to antidepressants for treatment-resistant depression.
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Samuele Cortese reports on a recent study of 13-25 year old people with ADHD, which looks at the comparative risk of psychosis during treatment with methylphenidate and amphetamines.
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Deenan Edward and Suhana Ahmed summarise a Scottish study of prescribing for bipolar disorder between 2009-2016, which identified a clear trend towards decreasing lithium use.
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This review of the the effectiveness of different antibiotic protocols to prevent early dental implant failure includes 9 RCTs showing that antibiotics were protective against early implant failures.
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Dean Connolly looks at an international study which asks: Is there consensus across evidence-based guidelines for the psychotropic drug management of bipolar disorder during the perinatal period?
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Keir Harding prepares for the #BIGSPD19 conference by reading Mike Crawford et al’s recent RCT on the clinical effectiveness and cost-effectiveness of lamotrigine in borderline personality disorder.
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