Salivary biomarkers for diagnosing periodontal disease

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This review of salivary biomarkers for diagnosing periodontal disease only identified 4 studies at high risk of bias but suggests a small number of potential biomarkers. However the findings should be interpreted with caution.

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Vertical root fracture diagnosis with CBCT – insufficient evidence

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Only 4 small studies at high risk of bias were available for this review of cone-beam computed tomography (CBCT) for diagnosis of vertical root fracture, providing insufficient evidence to suggest that CBCT is a reliable test.

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Cognitive tests for dementia: MMSE, Mini-Cog and ACE-R

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Akshay Nair explores the results of a systematic review of cognitive tests for dementia and mild cognitive impairment, which focuses on the MMSE, Mini-Cog, ACE-R and MoCA instruments. Along the way he explains how diagnostic tests work and how sensitivity and specificity are useful measures to get your head around.

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Oral Cancer – DNA-image cytometry may have promise for early detection

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This diagnostic review compared two computer aided adjunctive tests for oral cancer. Oral CDX and DNA-image cytometry. The results suggest that DNA-image cytometry has a highly significant potential over OralCDx brush biopsy as an accurate and simple diagnostic tool for clinically suspected oral precancer and oral cancer.

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Suicide risk assessment and intervention: need for a new approach?

A young man suffering from Social Anxiety stands alone as a group of people walk past rapidly

Olivia Kirtley and Alys Cole-King consider the implications of a new BMJ review on suicide risk assessment and intervention in people with mental illness.

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Root fracture detection with CBCT

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This review included 12 small in vitro and in vivo studies of Cone Beam Computed Tomography (CBCT) for the diagnosis of a root fracture. While the data suggest the ability to detect root fractures in non-endodontically treated teeth, the findings should be interpreted with caution.

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Does panoramic radiography predict nerve injury after third molar extraction?

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This review included 9 studies assessing the predictive value of panoramic radiography on inferior alveolar nerve (IAN) injury after third molar extraction. Results suggest that darkening of the root had a high specificity in predicting IAN injury.

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Radiographic caries detection is highly accurate for cavitated proximal lesions

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This review of 117 studies, which were mainly in vitro studies (93), found radiographic caries detection to be highly accurate for cavitated proximal lesions and also suitable to detect dentine caries lesions.

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Caries detection: visual detection has good accuracy

occlusal caries, molar teeth

This review included 102 studies the majority (77%) being laboratory-based findings that visual inspection had good caries detection accuracy in primary and permanent teeth, with a trend for higher specificity than sensitivity.

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Ultrasonography for diagnosing temporomandibular disorders

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This diagnostic test review included 11 studies the majority from 2 research groups. The findings suggest that ultrasonography could be useful for diagnosing anterior disk displacement in patients with temporomandibular disorders.

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