Atypical antipsychotics can lead to weight gain in children and adolescents, but more evidence needed about metabolic side effects

shutterstock_78370258

Atypical (second-generation) antipsychotics are used to treat a variety of psychiatric conditions. Although they have fewer side effects than first-generation antipsychotics, weight gain and other metabolic problems (such as high blood pressure and diabetes) remain common side effects of taking atypical antipsychotic medication (Mind, 2012). The Mental Elf has previously blogged about a Canadian report [read the full story…]

NICE publish new Quality Standard and Evidence Update on ADHD

Young girl riding bike

Attention Deficit Hyperactivity Disorder (ADHD) is the most common behavioural disorder in the UK, with sufferers experiencing inattentiveness, hyperactivity, and impulsivity. It is estimated to affect 3-9% of school aged children and young people in the UK (those aged 3 to 18), and 2% of adults worldwide (DSM-IV criteria). Typically ADHD will continue from childhood [read the full story…]

Systematic review finds that tricyclics do not benefit children with depression

A girl

Clinical depression is one of the most common mental health problems occurring in children and adolescents. It is often accompanied or followed by additional negative outcomes, including social and academic problems, anxiety and substance use. Many depressed adolescents continue to have recurring problems throughout adulthood. A variety of antidepressant drugs, such as tricyclics and selective [read the full story…]

New NICE TA: Aripiprazole for treating moderate to severe manic episodes in adolescents with bipolar I disorder

Pills

NICE has just published a new technology appraisal recommending aripiprazole as a treatment for bipolar disorder in young people. Technology Appraisals are systematic evaluations of the effectiveness of health technologies.  They do not have the broad scope of guidelines, which focus on topics rather than technologies, but they do give guidance for clinical practice on the [read the full story…]

Evidence-based youth psychotherapies: better than usual care, but only for less severe cases

Young people experiencing distress often fall through the cracks of a system built around diagnosis. Is treating the struggle, not the label, the answer?

Young people presenting with psychopathology may receive a wide range of treatments, such as family or cognitive behavioural therapy, skills training or behavioural contracting. Clearly it is important to know which of these interventions are best supported by evidence that they are effective in treating the presenting problem. Since some treatments have a significant evidence [read the full story…]

Observational study: antidepressant suicidality warnings may be counterproductive

Warning about pills

Selective serotonin reuptake inhibitors (SSRIs) have long been suspected to – paradoxically- increase suicidal behaviour in adolescent and pediatric patients. Consequently, national watchdogs started issuing black label warnings for all SSRIs to educate physicians and patients about associated risks. While clearly curbing the amount of antidepressant prescriptions, concerns have been voiced that this step has [read the full story…]

ADHD in childhood is not linked to later development of bipolar disorder

Child sitting under a tree

Bipolar disorder is considered a hereditary condition. There is emerging evidence that prodromes/early symptoms are evident in children before disorders develop. This potentially offers a chance to treat and prevent the development of mental health problems in adulthood. Being able to identifying early symptoms of the onset of this mental health disorder is clearly important, however, [read the full story…]

Talking therapy for teenagers (MBT-A) reduces self-harm and depression in self harming teens over a 12 month period

Young people skateboarding

In adults there is a growing body of evidence for psychotherapeutic interventions such as Transference Focussed Psychotherapy, Mentalization-Based Treatment and Dialectic Behavioural Therapy for patients who self harm. In the teenage population, there has been limited evidence to show that interventions are better than the treatment already provided. MBT has developed from psychodynamic psychotherapy and [read the full story…]

Are the current approaches to treating traumatised kids actually making them better?

Teddy bear in war zone

More and more research is telling us about the long-term negative consequences of trauma and adversity in childhood with correlations between childhood trauma and poor mental and physical health outcomes across the lifespan. So, it makes sense that there should be a good evidence base for treating the effects of childhood trauma. In February this [read the full story…]

Pay for performance improves treatment implementation, not outcomes, for adolescent substance use disorders

Money in the spotlight

The NHS has entered the era of GP-led commissioning of services, and providers will be required to submit data on key indicators such as quality of care and survival rates. This echoes some aspects of a 2001 report by the Institute of Medicine in the USA Crossing the Quality Chasm, which emphasised the need to [read the full story…]