Catherine Harmer summarises a recent network meta-analysis relating to her own Wellcome Trust funded research into antidepressants for young people with anxiety or depression.
[read the full story...]Experience of psychotropic medication and decision-making
Jennifer Rose Oulton reviews a qualitative study that explores the experiences of psychotropic medication use and decision-making for adults with learning disabilities and their carers.
[read the full story...]Botulinum toxin and idiopathic dentoalveolar pain
This review of the use of botulinum toxin (BONT-A) for pain-relief in patients with persistent idiopathic dentoalveolar pain included just 3 small uncontrolled studies providing a very limited amounh of very low quality evidence.
[read the full story...]Stopping antidepressants: patient perspectives on barriers and facilitators
Timothy Nyugen and Dafni Katsampa summarise a qualitative review of patient perspectives on the barriers and facilitators to stopping antidepressants.
[read the full story...]Mindfulness to support antidepressant withdrawal: patient views and experiences
Hannah Bowers writes her debut blog on a recent qualitative study, which explores how mindfulness-based cognitive therapy can help people stop taking antidepressants and recover from depression. This paper includes the views and perspectives of participants in the 2015 PREVENT trial.
[read the full story...]Cost-effectiveness of CBT for depression: uncertainty remains
Chris Sampson reviews a recent US study which looks at the cost-effectiveness of CBT versus second-generation antidepressants for the initial treatment of major depressive disorder.
[read the full story...]Are antidepressants safe? A new umbrella review of observational studies suggests they are, but we need more accurate data
Andrea Cipriani and Anneka Tomlinson scrutinise a brand new umbrella review of the associations between antidepressants and adverse health outcomes, which suggests that antidepressants are safe for most people who experience mental health difficulties.
[read the full story...]In adults with major depression, antidepressants may increase the risk of suicide
Douglas Badenoch explores a meta-analysis of follow-up data from clinical trials of antidepressants, which found a small but significant increase in suicide risk.
[read the full story...]Intranasal esketamine for treatment-resistant depression: the first clinical study
Jodi Rintelman writes her debut elf blog on the first randomised controlled trial on the efficacy and safety of intranasal esketamine as an adjunctive treatment to antidepressants for treatment-resistant depression.
[read the full story...]Medication for generalised anxiety disorder: new network meta-analysis
A group of UCL Masters Students summarise a recent network meta-analysis of drug treatment for generalised anxiety disorder, which finds that Venlafaxine, Pregabalin, Escitalopram and Duloxetine are all viable alternatives to Benzodiazepines.
[read the full story...]