This review of difference concentrations of hydrogen peroxide for in-office dental bleaching on colour change and bleaching sensitivity included 25 RCTs. The findings indicate that low and medium hydrogen peroxide concentrations had lower risk and intensity of bleaching sensitivity and no difference in colour change efficacy compared with high concentrations.
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Manas Dave considers this review of the safety and reliability of digital pathology. The review included 24 studies showing high concordance between digital pathology and light microscopy suggesting that digital pathology is a viable alternative to light microscopy.
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This review of the effectiveness of removable complete denture disinfection using microwaves for the treatment of denture stomatitis included 3 small RCTs. While the findings suggest that microwave may be effective the evidence is of low certainty so additional high quality well reported studies are needed.
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In his first blog for the Dental Elf Rajpal Tattar take a look at a review of the diagnostic accuracy of salivary biomarkers for the detection of oral squamous cell carcinoma (OSCC). The review considers two biomarkers, cytokeratin 19 fragment (CYFRA 21-1) and for matrix metalloproteinase-9 (MMP-9) but there is no conclusive evidence for either at present.
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11 RCTs were included in this Cochrane review which looked at the relative effectiveness of fissure sealants compared with fluoride varnishes for the prevention of caries in the occlusal surfaces of permanent teeth.
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This review of metastasis to the oral and maxillofacial region included 217 studies (190 case reports,24 case series ). Metastasis were uncommon, but identified from 29 primary sites, the most common sites being lung the lungs (20.97%), breast (12.06%) and kidney (11.78%).
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This review of the effect of powered and manual toothbrushes on oral health during fixed applinace orthodontic treatment included 7 RCTs. The findings suggest no diference between the toothbrush types. However the quality of the evidence is low and the studies are of short duration.
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This review of sub-gingival chlorhexidine chips as an adjunct to scaling and root planing in patients with chronic periodontitis included 15 RCTs involving 620 patients in total. Findings suggest an additional improvement with adjunctive use of chlorhexidine chips.
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The review of the use of botulinum toxin type A injections in the management of primary bruxism in adults included 10 studies. Only 6 of the included studies were RCTs and the studies were generally small are very hetrogeneous so additional well designed and conducted RCTs are needed.
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Jennifer Lau summarises a recent systematic review relating to her own Wellcome Trust funded research into promoting helpful attention and interpretation patterns to reduce anxiety and depression in young people.
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