Results: 2605

For: systematic review

Another review finds limited evidence for making treatment recommendations for keratocystic odontogenic tumors

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The keratocystic odontogenic tumor (KCOT) is a benign but locally aggressive tumour and accounts for 2-11% of jaw cysts and can occur at any age. Historically they have been referred to as odontogenic keratocyst (OKC) and primordial cyst. A range of treatment approaches have been suggested for KCOTs but preferred option is still debatable. The [read the full story…]

And if we do nothing? A new systematic review explores natural PTSD remission rates

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Who naturally recovers from PTSD and why? A recent meta-regression analysis finds an overall natural remission rate for PTSD of 44%, with no increase in remission after longer observation periods.

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Insufficient evidence to determine the effect of systemic antibiotics on adults with symptomatic apical periodontitis or acute apical abscess

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The recommended treatment for apical periodontitis or acute apical abscess is removal of the source of inflammation or infection by local, operative measures ie tooth extraction or pulp extirpation possibly in combination with the incision and drainage of any swelling present. Antibiotics are only recommended where there is evidence of spreading infection or systemic symptoms.   [read the full story…]

Health effects of depression: keeping economists’ models on track

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Health Economist Christopher Sampson reports on a recent systematic review and meta-analysis, which shows health-related quality of life utility values vary between studies and economic models should consider this.

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Periodontal treatment may be effective in improving metabolic control in diabetics but clinical significance is unclear

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The destructive form of periodontal disease, periodontitis, affects approximately 50% of adults and over 60% of over 65 year olds, with severe periodontitis affecting 10–15% of populations. It is biologically plausible that chronic inflammation from periodontal disease has an impact on diabetes control and a number of epidemiological studies have highlighted associations between the two [read the full story…]

Little reliable evidence available to assess if dental implant failure is higher in diabetic patients

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Diabetics have been shown to have a higher frequency of periodontal disease and tooth loss. This together with the fact that diabetics also have delayed wound healing means that dental implant placement is more risky in these patients. The aim of this review was to investigate whether there are any effects of diabetes mellitus on [read the full story…]

How does buprenorphine fair as an alternative to methadone for treating opioid dependence?

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Meg Fluharty summarises a recent Cochrane review, which tells us that high-dose buprenorphine is an effective maintenance treatment for heroin compared to placebo, but fixed flexible-dosing methadone is superior to buprenorphine at participant retention.

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Limited evidence to make recommendations about initial archwires or specific archwire sequences for orthodontic treatment

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The aim of this review was to assess the effectiveness, efficiency, and potential side effects of the various archwires used during fixed appliance orthodontic treatment. Searches were conducted in Medline, Cochrane Library, Biomed Central, BBO including LILACS, Ind Med, Sceilo, Clinical trials.gov, Conference paper Index, Digital Dissertations, German National Library of Medicine (ZB MED), Google [read the full story…]

Watching what you eat: does mindfulness work for binging and weight loss?

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Helen Bould tells us that mindfulness may do many things, and is queuing up to take its place with CBT as the panacea of mental illness, but in her view it cannot yet lay claim to solving binge eating.

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Passive smoking and periodontal disease- little evidence currently available of a link

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The strong association between smoking and periodontal disease is known (Dental Elf 20th June 2014). However as non-smoking individuals exposed to environmental tobacco smoke (passive or second- hand smoking) are also know to be at risk of disease this review aimed to assess the association between environmental tobacco smoke (ETS) and periodontal disease. Searches were [read the full story…]