Results: 2600

For: systematic review

Root canal treatment outcomes and pulpal status

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This review comparing the effectiveness of root canal treatment outcomes in teeth with a vital pulp versus a necrotic pulp included 28 studies. No differences between vital and necrotic pulps were seen for tooth survival. No studies reported on tooth function, adverse effects or oral health related quality of life (OHRQoL).

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Photodynamic therapy in primary teeth root canal therapy?

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This review of the efficacy of adjunctive photodynamic therapy (PDT) on root canal treatment in primary teeth included 4 studies. The included studies were small and of short duration and lacked clinically relevant outcomes. Larger high quality well conducted studies with follow up periods of at least 12 months are needed to assess the role of PDT in primary teeth.

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Cellular immune phenotypes of depression: a gateway to precision medicine 

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In her debut blog, Fabiana Corsi-Zuelli summarises a recent systematic review and meta-analysis investigating the role of peripheral immune cells in depression, with a focus on implications for future immunotherapy trials.

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Pulpotomy in permanent teeth with bioactive materials

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This review evaluating the evaluate the success rate of pulpotomies on permanent teeth using ProRoot MTA, compared to calcium hydroxide or other bioceramic cements included 16 RCTs. The findings suggest better outcomes with MTA than calcium hydroxide. However 10 of the studies were at high risk of bias and the overall certainty of evidence was assessed as low.

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The international prevalence of suicidal ideation and behaviour in youth

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Lucy Barrass summarises a systematic review published in the Journal of the American Academy of Child & Adolescent Psychiatry that explores the international prevalence of suicidal ideation and behaviour among young people across global regions.

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Helmet use and maxillofacial injuries due to bicycle and scooter accidents

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This review of the effect of helmet use on the incidence of maxillofacial injuries due to cycling, e-bike, scooter, and e- scooter accidents included 14 studies. The findings suggest a significant reduction in the risk of maxillofacial injury with helmet use Odds ratio = 0.682 (95%CI; 0.565 to 0.822). Although all but 2 of the studies were retrospective and only 5 studies were considered to be of high quality .

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Non‐surgical procedures to accelerate orthodontic tooth movement

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This Cochrane review update was to assess the effect of non‐surgical adjunctive interventions on the rate of orthodontic tooth movement and the overall duration of treatment included 23 RCTs.The findings suggest there may be limited benefit from photobiomodulation application for accelerating discrete treatment phases but this should be interpreted very cautiously as the findings may not be clinically important and the evidence is of low to very low certainty.

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Interventions to foster resilience in nursing staff may help (a little) in the short-term

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Olga Lainidi summarises a recent systematic review and meta-analysis investigating the effectiveness of resilience interventions on the mental health of nursing staff.

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Add on iCBT: weak evidence of modest benefits in depression and anxiety

iCBT can be effective in reducing symptoms of depression, anxiety, OCD and PTSD - could its accessibility help reach more people?

Liesbeth Tip and Antigone Lanitis reflect on a recent systematic review and meta-analysis that investigated internet-delivered psychological treatment as an add-on to treatment as usual in depression, anxiety, and PTSD.

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Orthodontically induced external apical root resorption

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This review comparing orthodontically induced external apical root resorption (EARR) in root-filled teeth and vital pulp teeth included 11 mainly retrospective studies . The findings suggest less EARR in root-filled teeth but the evidence is of very low certainty.

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