John Baker summarises a recent Cochrane systematic review of psychosocial interventions for benzodiazepine harmful use, abuse or dependence.
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John Baker summarises a recent Cochrane systematic review of psychosocial interventions for benzodiazepine harmful use, abuse or dependence.
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This review included 8 RCTs involving a total of 476 patients and found that submucosal dexamethasone reduced postoperative pain and swelling. Although only one of the studies was at low risk of bias and there was a possibility of publication bias, the findings should be considered with caution.
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Thirteen studies were included in this review of medication related osteonecrosis of the jaw. The majority were case series ( 9) with the risk of osteonecrosis after tooth extraction being higher in those taking IV bisphosphonates ( 3.2% (95% CI: 1.7–4.7%) than those on oral bisphosphonates 0.15% (95% CI: 0.0–0.36%).
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Only 18 studies were identified for this review of caries risk assessment models. Previous caries experience and salivary mutans streptococci levels were the only two methods with more than 3 studies and the quality of evidence for these two approaches was low.
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This review of the use of Calcium Sodium Phosphosilicate (CSPS) for the treatment of dentine hypersensitivity included 11 trials involving a total of 1190 patients suggesting that a 5% CSPS-containing toothpaste is effective for use as an at-home treatment.
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63 studies were included in the review of the association between breastfeeding and caries. The majority (73%) were cross-sectional. The findings suggest that breastfeeding up to 12 months of age is not associated with an increased risk of dental caries and in fact may offer some protection compared with formula.
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This update of a 2010 Cochrane review found low quality evidence that periodontal treatment involving scaling and root planing does improve glycaemic control in people with diabetes, with a mean percentage reduction in HbA1c of 0.29% at 3-4 months, but there is insufficient evidence to demonstrate that this is maintained after 4 months.
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Leen Vereenooghe summarises a systematic review of the use of CBT (cognitive behavioural therapy) to treat depression in people with learning disabilities.
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While there are a number of reviews of treatment options for the keratocystic odontogenic tumour (KCOT), this update of a Cochrane review could identify no relevant RCTs of treatment options. So there is a clear need for well designed and conducted randomised controlled trials to evaluate treatments for KCOTs.
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8 trials involving a total of 365 patients were included in this Cochrane review of micro-invasive treatments for proximal caries. Micro-invasive treatment significantly reduced the odds of lesion progression compared with non-invasive treatment (e.g fluoride varnish) or oral hygiene advice (e.g to floss) OR=0.24, (95% CI; 0.14 to 0.41).
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