This review of the evidence on possible association between locally delivered nicotine replacement therapy(NRT) and oral side effects included 28 RCTs. Most of the RCTs were at high risk of bias mainly because of allocation concealment concerns. Reported oral side effects including oral soreness, gastric reflux or vomiting, and mouth or throat irritation.
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In this blog Carly Ross takes a look at a review of the oral manifestations of Huntington’s disease (HD) which included 22 studies published between 1992 and 2021.
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This review comparing the outcomes of , CAD-CAM removable complete dentures (CDs) with conventional CDs included 73 studies. A majority of the studies were in-vitro small, and involved multiple comparison. 39 studies contributed to meta-analyses of a broad range of parameters whiich suggest little technical difference between CAD-CAM and conventional CDs. However few studies reported on aesthetics or patient reported outcomes.
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28 mainly retrospective studies were included in this review which aimed to determine if tooth extraction prior to head and neck radiotherapy (RT )is associated with a reduced risk of developing osteoradionectosis (ORN). The findings showed a significant association of post-RT dental extractions with the risk of ORN development, odds ratio = 1.98 (95%CI: 1.17 to 3.35. However the certainty of the evidence was low to moderate.
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This review of whether children and adolescents with attention deficit with hyperactivity disorder (ADHD) had more dental caries than children and adolescents without ADHD included 13 observational studies. The findings suggest a higher risk of caries in children with ADHD Odds ratio = 3.31(95%CI; 1.25 to 8.73) and a significantly higher DMFT index Mean difference = 0.75 (0.38 to 1.13). However because of heterogeneity in the included study designs and a lack of adjustments for confounding factors the findings should be interpreted cautiously.
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This review examining the association between oral manifestations and the use of oral piercings included 54 studies. Damage to periodontal health and tooth structure were the most commonly reported complications however the quality of the evidence is of very low certainty.
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This review of the efficacy of oscillating-rotating power toothbrush compared to high-frequency sonic power toothbrush includes 32 RCTs. The findings show moderate certainty evidence in favour of the oscillating-rotating however the clinical relevance may not be important.
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This Cochrane review update comparing full-mouth scaling/disinfection (FMS/D) to conventional quadrant scaling for periodontitis for the treatment of periodontitis included 20 RCTs. However there is still no clear evidence that FMS/D approaches provide additional clinical benefit compared to conventional treatment.
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This review investigating whether the presence of third molars during sagittal split osteotomy of the mandible increases the risk of complications included 15 studies. The findings suggests no statistically significant relationship between the presence of 3Ms and complications. However a majority of the studies were retrospective with 13 studies being considered to be at high risk of bias so the certainty of the evidence is considered to be very low.
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This review assessing a potential association between early childhood caries (ECC) and iron deficiency anaemia (IDA) included 14 studies. While the findings showed an association between ECC and IDA the certainty of the evidence was very low so the findings should be interpreted very cautiously,
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