Thirteen studies were included in this review of medication related osteonecrosis of the jaw. The majority were case series ( 9) with the risk of osteonecrosis after tooth extraction being higher in those taking IV bisphosphonates ( 3.2% (95% CI: 1.7–4.7%) than those on oral bisphosphonates 0.15% (95% CI: 0.0–0.36%).
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Only 18 studies were identified for this review of caries risk assessment models. Previous caries experience and salivary mutans streptococci levels were the only two methods with more than 3 studies and the quality of evidence for these two approaches was low.
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This review of the use of Calcium Sodium Phosphosilicate (CSPS) for the treatment of dentine hypersensitivity included 11 trials involving a total of 1190 patients suggesting that a 5% CSPS-containing toothpaste is effective for use as an at-home treatment.
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63 studies were included in the review of the association between breastfeeding and caries. The majority (73%) were cross-sectional. The findings suggest that breastfeeding up to 12 months of age is not associated with an increased risk of dental caries and in fact may offer some protection compared with formula.
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This update of a 2010 Cochrane review found low quality evidence that periodontal treatment involving scaling and root planing does improve glycaemic control in people with diabetes, with a mean percentage reduction in HbA1c of 0.29% at 3-4 months, but there is insufficient evidence to demonstrate that this is maintained after 4 months.
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While there are a number of reviews of treatment options for the keratocystic odontogenic tumour (KCOT), this update of a Cochrane review could identify no relevant RCTs of treatment options. So there is a clear need for well designed and conducted randomised controlled trials to evaluate treatments for KCOTs.
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8 trials involving a total of 365 patients were included in this Cochrane review of micro-invasive treatments for proximal caries. Micro-invasive treatment significantly reduced the odds of lesion progression compared with non-invasive treatment (e.g fluoride varnish) or oral hygiene advice (e.g to floss) OR=0.24, (95% CI; 0.14 to 0.41).
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The concept of the shortened dental arch was first raised as a concept 30 years ago, with the WHO endorsing a functional dentition of 20 functional teeth without resorting to a prosthesis. This large cross-sectional study from Brazil suggests that having a shortened dental arch does not have any significant impact on oral health related quality of life.
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In her debut blog, Jacqueline Burns considers a school-based cluster RCT, which demonstrated a small short-term improvement on oral self-care, using a social-cognitive theory based intervention.
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This trial of the effects of primer on the bracket failure rate in orthodontic patients involved 49 patients, using a cross-mouth design; and found fewer bonding failures in the non-primer group 5.5%, compared with 3.1% in primer setting and adjusted odd ratio of 1.89 (95% CI 0.97–3.68).
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