Results: 1707

For: Treatment

Treating ADHD in psychosis: What does the evidence say about safety?

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How safe is it to treat ADHD in people with schizophrenia spectrum disorders? New long-term data offers pragmatic reassurance, but also some warnings.

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Clozapine and infection risk: new evidence from Hong Kong’s 20-year cohort study

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Clozapine is described as the gold standard treatment for schizophrenia but a new cohort study suggests it is associated with an increased risk of infections, particularly in older patients, further solidifying the case for holistic care.

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From menstruation to menopause: how sex-steroids shape women’s mental health across the life course

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Sex and gender differences in mental health are real; the mechanisms are under-explored. This review pulls together evidence on sex-steroids, brain development, neuroinflammation, and the social world to show where practice and policy must catch up.

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Ketamine, depression and childhood trauma: new evidence from a community study

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Can ketamine help people with treatment-resistant depression, regardless of childhood trauma history? This new study suggests that trauma load and severity may not influence treatment outcomes.

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Widening the lens on delusions: a global meta-analysis shows our scales miss many common themes

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This big meta-analysis pooled 155 studies from 37 countries and found many more delusional themes than standard assessment tools capture. Clinicians should watch for “non-classical” content, and researchers should widen how we measure delusions.

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Therapy through the lens of autism: what helps autistic adults feel safe and supported?

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What makes therapy feel safe and effective for autistic adults? This new qualitative study sheds light on the adjustments that matter most.

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Prescribing in borderline personality disorder: Evidence, relationships, and the realities of practice

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No drugs are officially approved for borderline personality disorder, yet prescribing is widespread. This systematic review explores why clinicians prescribe, the pressures they face, and what it means for patient care.

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The genetic link behind sleep problems, cognitive dysfunction, and neuroticism in ‘treatment-resistant depression’

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A big new study suggests that certain genetic traits—like insomnia risk and neuroticism—may make depression harder to treat, while protective traits include education and cognitive ability.

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Targeting teenage worry: network analysis of anxiety symptoms over time

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Nervousness, irritability, excessive worry, uncontrollable worry… not all anxiety symptoms weigh the same at different ages. This new Chineses study shows how anxiety networks tighten as young people grow older, and where the best intervention targets may lie.

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Closing the care gap: Why so few people with mental disorders receive effective treatment worldwide

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Effective treatment for mental health disorders remains the exception rather than the rule. A new 21-country study reveals where in the treatment cascade people are most likely to drop out and which factors improve the odds of getting the care they need.

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