How can genetics help us better understand, diagnose and treat mental illness? An interview with Andrew McIntosh


This World Mental Health Day, we share a Wellcome Trust interview with Professor Andrew McIntosh, who has a £4.7 million award to explore why people develop depression. He tells Wellcome how he hopes his work will improve the lives of people with mental health conditions, and how he looks after his own mental wellbeing.

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Long duration of untreated psychosis is associated with a range of poor outcomes


Joe Judge appraises a recent systematic review and meta-analysis looking at the duration of untreated psychosis as a predictor of long-term outcomes in schizophrenia.

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Orthodontic treatment; can it be accelerated by surgical and non-surgical approaches?

iStock_000002259334XSmall braces on teeth

With typical orthodontic treatment taking 18-24 months there is pressure to reduce the time it takes. This review considers a range of potential options but there is limited quality evidence for most of the techniques identified.

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Similarities found in characteristics of juvenile offenders with and without learning disabilities

Individuals more likely to be arrested or taken to ED if living indpependently or with family

This study from the Netherlands looked at whether it is possible to determine differences in personal characteristics and functioning between juvenile offenders under mandatory treatment orders who had a measured IQ of less than 70, between 70 and 85 and over 85. The authors were hoping to offer advice and guidance on ways to better [read the full story…]